| Форма представления | Статьи в зарубежных журналах и сборниках |
| Год публикации | 2023 |
| Язык | русский |
|
Биктемирова Раиса Габдулловна, автор
Зефиров Тимур Львович, автор
Зиятдинова Нафиса Ильгизовна, автор
|
|
Леонова Алина Маратовна, автор
Шакиров Ранис Ришатович, автор
|
| Библиографическое описание на языке оригинала |
Galieva A.M. Peculiarities of AP repolarization in cardiomyocytes of
three-week-old rats during application of clonidine hydrochloride / A.M. Galieva , N.I. Ziyatdinova ,R.R. Shakirov , R.G. Biktemirova,T.L. Zefrov // |
| Аннотация |
Activation of the sympathetic nervous system is responsible for the body's “fght or fight” reaction. The physiological responses to the activation of the sympathetic nervous system and adrenal medulla are mediated through the action of the endogenous catecholamines norepinephrine (or noradrenaline) and epinephrine (or adrenaline) on adrenergic receptors. Adrenergic receptors belong to the superfamily of G protein-coupled receptors (GPCR). Adrenoceptors are divided into alpha1, alpha2, beta1, beta2 and beta3 receptors. α2 receptors are coupled to inhibitory Gi proteins, that inactivate adenylyl cyclase, decreasing cyclic adenosine monophosphate (AMP) production. In addition to the endogenous ligands epinephrine and norepinephrine, they may be activated by several agonist drugs, including clonidine, brimonidine, and moxonidine. |
| Ключевые слова |
cardiomyocytes, three-week-old rats, clonidine hydrochloride |
| Название журнала |
Biophysical Reviews
|
| URL |
https://link.springer.com/article/10.1007/s12551-023-01150-w |
| Пожалуйста, используйте этот идентификатор, чтобы цитировать или ссылаться на эту карточку |
https://repository.kpfu.ru/?p_id=290517 |
| Файлы ресурса | |
|
|
Полная запись метаданных  |
| Поле DC |
Значение |
Язык |
| dc.contributor.author |
Биктемирова Раиса Габдулловна |
ru_RU |
| dc.contributor.author |
Зефиров Тимур Львович |
ru_RU |
| dc.contributor.author |
Зиятдинова Нафиса Ильгизовна |
ru_RU |
| dc.contributor.author |
Леонова Алина Маратовна |
ru_RU |
| dc.contributor.author |
Шакиров Ранис Ришатович |
ru_RU |
| dc.date.accessioned |
2023-01-01T00:00:00Z |
ru_RU |
| dc.date.available |
2023-01-01T00:00:00Z |
ru_RU |
| dc.date.issued |
2023 |
ru_RU |
| dc.identifier.citation |
Galieva A.M. Peculiarities of AP repolarization in cardiomyocytes of
three-week-old rats during application of clonidine hydrochloride / A.M. Galieva , N.I. Ziyatdinova ,R.R. Shakirov , R.G. Biktemirova,T.L. Zefrov // |
ru_RU |
| dc.identifier.uri |
https://repository.kpfu.ru/?p_id=290517 |
ru_RU |
| dc.description.abstract |
Biophysical Reviews |
ru_RU |
| dc.description.abstract |
Activation of the sympathetic nervous system is responsible for the body's “fght or fight” reaction. The physiological responses to the activation of the sympathetic nervous system and adrenal medulla are mediated through the action of the endogenous catecholamines norepinephrine (or noradrenaline) and epinephrine (or adrenaline) on adrenergic receptors. Adrenergic receptors belong to the superfamily of G protein-coupled receptors (GPCR). Adrenoceptors are divided into alpha1, alpha2, beta1, beta2 and beta3 receptors. α2 receptors are coupled to inhibitory Gi proteins, that inactivate adenylyl cyclase, decreasing cyclic adenosine monophosphate (AMP) production. In addition to the endogenous ligands epinephrine and norepinephrine, they may be activated by several agonist drugs, including clonidine, brimonidine, and moxonidine. |
ru_RU |
| dc.language.iso |
ru |
ru_RU |
| dc.subject |
cardiomyocytes |
ru_RU |
| dc.subject |
three-week-old rats |
ru_RU |
| dc.subject |
clonidine hydrochloride |
ru_RU |
| dc.title |
Peculiarities of AP repolarization in cardiomyocytes of
three-week-old rats during application of clonidine hydrochloride |
ru_RU |
| dc.type |
Статьи в зарубежных журналах и сборниках |
ru_RU |
|
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