| Форма представления | Статьи в зарубежных журналах и сборниках |
| Год публикации | 2023 |
| Язык | английский |
|
Андрианов Вячеслав Вадимович, автор
Богодвид Татьяна Халиловна, автор
Гайнутдинов Халил Латыпович, автор
Дерябина Ирина Борисовна, автор
Муранова Людмила Николаевна, автор
Силантьева Динара Ирековна, автор
|
| Библиографическое описание на языке оригинала |
Andrianov, V.V.; Kulchitsky, V.A.; Yafarova, G.G.; Bazan, L.V.; Bogodvid, T.K.; Deryabina, I.B.; Muranova, L.N.; Silantyeva, D.I.; Arslanov, A.I.; Paveliev, M.N.; et al. Investigation of NO Role in Neural Tissue in Brain and Spinal Cord Injury. Molecules 2023, 28, 7359. https://doi.org/10.3390/molecules28217359 |
| Аннотация |
Nitric oxide (NO) production in injured and intact brain regions was compared by EPR spectroscopy in a model of brain and spinal cord injury in Wistar rats. The precentral gyrus of the brain was injured, followed by the spinal cord at the level of the first lumbar vertebra. Seven days after brain injury, a reduction in NO content of 84% in injured brain regions and 66% in intact brain regions was found. The difference in NO production in injured and uninjured brain regions persisted 7 days after injury. The copper content in the brain remained unchanged one week after modeling of brain and spinal cord injury. The data obtained in the experiments help to explain the problems in the therapy of patients with combined brain injury. |
| Ключевые слова |
nitric oxide; cooper; brain stroke; spinal cord injury; electron paramagnetic resonance |
| Название журнала |
Molecules
|
| URL |
https://www.mdpi.com/1420-3049/28/21/7359 |
| Пожалуйста, используйте этот идентификатор, чтобы цитировать или ссылаться на эту карточку |
https://repository.kpfu.ru/?p_id=290704 |
| Файлы ресурса | |
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Полная запись метаданных  |
| Поле DC |
Значение |
Язык |
| dc.contributor.author |
Андрианов Вячеслав Вадимович |
ru_RU |
| dc.contributor.author |
Богодвид Татьяна Халиловна |
ru_RU |
| dc.contributor.author |
Гайнутдинов Халил Латыпович |
ru_RU |
| dc.contributor.author |
Дерябина Ирина Борисовна |
ru_RU |
| dc.contributor.author |
Муранова Людмила Николаевна |
ru_RU |
| dc.contributor.author |
Силантьева Динара Ирековна |
ru_RU |
| dc.date.accessioned |
2023-01-01T00:00:00Z |
ru_RU |
| dc.date.available |
2023-01-01T00:00:00Z |
ru_RU |
| dc.date.issued |
2023 |
ru_RU |
| dc.identifier.citation |
Andrianov, V.V.; Kulchitsky, V.A.; Yafarova, G.G.; Bazan, L.V.; Bogodvid, T.K.; Deryabina, I.B.; Muranova, L.N.; Silantyeva, D.I.; Arslanov, A.I.; Paveliev, M.N.; et al. Investigation of NO Role in Neural Tissue in Brain and Spinal Cord Injury. Molecules 2023, 28, 7359. https://doi.org/10.3390/molecules28217359 |
ru_RU |
| dc.identifier.uri |
https://repository.kpfu.ru/?p_id=290704 |
ru_RU |
| dc.description.abstract |
Molecules |
ru_RU |
| dc.description.abstract |
Nitric oxide (NO) production in injured and intact brain regions was compared by EPR spectroscopy in a model of brain and spinal cord injury in Wistar rats. The precentral gyrus of the brain was injured, followed by the spinal cord at the level of the first lumbar vertebra. Seven days after brain injury, a reduction in NO content of 84% in injured brain regions and 66% in intact brain regions was found. The difference in NO production in injured and uninjured brain regions persisted 7 days after injury. The copper content in the brain remained unchanged one week after modeling of brain and spinal cord injury. The data obtained in the experiments help to explain the problems in the therapy of patients with combined brain injury. |
ru_RU |
| dc.language.iso |
ru |
ru_RU |
| dc.subject |
|
ru_RU |
| dc.title |
Investigation of NO Role in Neural Tissue in Brain and Spinal Cord Injury |
ru_RU |
| dc.type |
Статьи в зарубежных журналах и сборниках |
ru_RU |
|
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