Форма представления | Статьи в зарубежных журналах и сборниках |
Год публикации | 2023 |
Язык | английский |
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Кубышева Наиля Исхаковна, автор
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Eliseeva Tatyana , автор
Karaulov Alexandr , автор
Khrapunova Ekaterina , автор
Novikov Viktor , автор
Ovsyannikov Dmitry , автор
Postnikova Larisa , автор
Soodaeva Svetlana , автор
Stroganov Andrey , автор
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Библиографическое описание на языке оригинала |
Kubysheva N.I., Postnikova L.B., Novikov V.V., Soodaeva S.K., Eliseeva T.I., Khrapunova E.I., Stroganov A.B., Ovsyannikov D.Yu., Karaulov A.V.. Functional Activity of Blood Neutrophils in Patients with Stable Course and Exacerbation of Chronic Obstructive Pulmonary Disease. Bull Exp Biol Med, 176, 26–29 (2023). |
Аннотация |
A comparative study of the parameters of chemiluminescence (CL) of blood neutrophils in patients with varying degrees of severity of chronic obstructive pulmonary disease (COPD) in different periods of the disease was carried out. The maximum values of induced and spontaneous CL were recorded at moderate severity of the disease during exacerbation. Low levels of CL indicators were found in severe COPD in stable phase. The values of the induction period of the chemiluminescent response in patients with moderate COPD were higher compared with the control group. Correlations between the values of induced chemiluminescence of neutrophils and the indicator of respiration function FEV1 were established, which may indicate the influence of multidirectional changes in the functional activity of systemic neutrophils on the development and worsening of airway obstruction in COPD patients. |
Ключевые слова |
COPD; chemiluminescence; neutrophils |
Название журнала |
Bulletin of Experimental Biology and Medicine
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URL |
https://link.springer.com/article/10.1007/s10517-023-05960-6 |
Пожалуйста, используйте этот идентификатор, чтобы цитировать или ссылаться на эту карточку |
https://repository.kpfu.ru/?p_id=293459 |
Файлы ресурса | |
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Полная запись метаданных |
Поле DC |
Значение |
Язык |
dc.contributor.author |
Кубышева Наиля Исхаковна |
ru_RU |
dc.contributor.author |
Eliseeva Tatyana |
ru_RU |
dc.contributor.author |
Karaulov Alexandr |
ru_RU |
dc.contributor.author |
Khrapunova Ekaterina |
ru_RU |
dc.contributor.author |
Novikov Viktor |
ru_RU |
dc.contributor.author |
Ovsyannikov Dmitry |
ru_RU |
dc.contributor.author |
Postnikova Larisa |
ru_RU |
dc.contributor.author |
Soodaeva Svetlana |
ru_RU |
dc.contributor.author |
Stroganov Andrey |
ru_RU |
dc.date.accessioned |
2023-01-01T00:00:00Z |
ru_RU |
dc.date.available |
2023-01-01T00:00:00Z |
ru_RU |
dc.date.issued |
2023 |
ru_RU |
dc.identifier.citation |
Kubysheva N.I., Postnikova L.B., Novikov V.V., Soodaeva S.K., Eliseeva T.I., Khrapunova E.I., Stroganov A.B., Ovsyannikov D.Yu., Karaulov A.V.. Functional Activity of Blood Neutrophils in Patients with Stable Course and Exacerbation of Chronic Obstructive Pulmonary Disease. Bull Exp Biol Med, 176, 26–29 (2023). |
ru_RU |
dc.identifier.uri |
https://repository.kpfu.ru/?p_id=293459 |
ru_RU |
dc.description.abstract |
Bulletin of Experimental Biology and Medicine |
ru_RU |
dc.description.abstract |
A comparative study of the parameters of chemiluminescence (CL) of blood neutrophils in patients with varying degrees of severity of chronic obstructive pulmonary disease (COPD) in different periods of the disease was carried out. The maximum values of induced and spontaneous CL were recorded at moderate severity of the disease during exacerbation. Low levels of CL indicators were found in severe COPD in stable phase. The values of the induction period of the chemiluminescent response in patients with moderate COPD were higher compared with the control group. Correlations between the values of induced chemiluminescence of neutrophils and the indicator of respiration function FEV1 were established, which may indicate the influence of multidirectional changes in the functional activity of systemic neutrophils on the development and worsening of airway obstruction in COPD patients. |
ru_RU |
dc.language.iso |
ru |
ru_RU |
dc.subject |
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ru_RU |
dc.title |
Functional Activity of Blood Neutrophils in Patients with Stable Course and Exacerbation of Chronic Obstructive Pulmonary Disease |
ru_RU |
dc.type |
Статьи в зарубежных журналах и сборниках |
ru_RU |
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