| Форма представления | Статьи в зарубежных журналах и сборниках |
| Год публикации | 2024 |
| Язык | русский |
|
Зинченко Сергей Викторович, автор
Сафин Дамир Ильясович, автор
|
| Библиографическое описание на языке оригинала |
Khusainova, A.I.Photo- and X-ray Induced Cytotoxicity of CeF3-YF3-TbF3 Nanoparticle-Polyvinylpyrrolidone—“Radachlorin” Composites for Combined Photodynamic Therapy / A.I. Khusainova, A.S. Nizamutdinov, N.I. Shamsutdinov, S.Kalinichenko, D.I. Safin, M. Gafurov, E.V. Lukinova, S.Kh. Batygov, S. V. Kuznetsov, S.V. Zinchenko, P.V. Zelenikhin, M. Pudovkin // Materials.- 2024, -№17, 316.-з.1-14
|
| Аннотация |
The Ce0.5Y0.35Tb0.15F3 nanoparticles with a CeF3 hexagonal structure were synthesized
using the co-precipitation technique. The average nanoparticle diameter was 14 ? 1 nm. The luminescence decay curves of the Ce0.5Y0.35Tb0.15F3 nanoparticles (λem = 541 nm, 5D4–
7F5
transition of Tb3+)
conjugated with Radachlorin using polyvinylpyrrolidone coating as well as without Radachlorin
were detected. Efficient nonradiative energy transfer from Tb3+ to the Radachlorin was demonstrated.
The maximum energy transfer coefficients for the nanoparticles conjugated with Radachlorin via
polyvinylpyrrolidone and without the coating were 82% and 55%, respectively. The average distance
between the nanoparticle surface and Radachlorin was R0 = 4.5 nm. The best results for X-ray-induced
cytotoxicity were observed for the NP-PVP-Rch sample at the lowest Rch concentration. In particular,
after X-ray irradiation, the survival of A549 human lung carcinoma cells decreased by ~12%. |
| Ключевые слова |
photodynamic therapy; combined photodynamic therapy; Radachlorin; nanoparticlephotosensitizer conjugates |
| Название журнала |
Materials
|
| URL |
https://doi.org/10.3390/ma17020316 |
| Пожалуйста, используйте этот идентификатор, чтобы цитировать или ссылаться на эту карточку |
https://repository.kpfu.ru/?p_id=294070 |
| Файлы ресурса | |
|
|
Полная запись метаданных  |
| Поле DC |
Значение |
Язык |
| dc.contributor.author |
Зинченко Сергей Викторович |
ru_RU |
| dc.contributor.author |
Сафин Дамир Ильясович |
ru_RU |
| dc.date.accessioned |
2024-01-01T00:00:00Z |
ru_RU |
| dc.date.available |
2024-01-01T00:00:00Z |
ru_RU |
| dc.date.issued |
2024 |
ru_RU |
| dc.identifier.citation |
Khusainova, A.I.Photo- and X-ray Induced Cytotoxicity of CeF3-YF3-TbF3 Nanoparticle-Polyvinylpyrrolidone—“Radachlorin” Composites for Combined Photodynamic Therapy / A.I. Khusainova, A.S. Nizamutdinov, N.I. Shamsutdinov, S.Kalinichenko, D.I. Safin, M. Gafurov, E.V. Lukinova, S.Kh. Batygov, S. V. Kuznetsov, S.V. Zinchenko, P.V. Zelenikhin, M. Pudovkin // Materials.- 2024, -№17, 316.-з.1-14
|
ru_RU |
| dc.identifier.uri |
https://repository.kpfu.ru/?p_id=294070 |
ru_RU |
| dc.description.abstract |
Materials |
ru_RU |
| dc.description.abstract |
The Ce0.5Y0.35Tb0.15F3 nanoparticles with a CeF3 hexagonal structure were synthesized
using the co-precipitation technique. The average nanoparticle diameter was 14 ? 1 nm. The luminescence decay curves of the Ce0.5Y0.35Tb0.15F3 nanoparticles (λem = 541 nm, 5D4–
7F5
transition of Tb3+)
conjugated with Radachlorin using polyvinylpyrrolidone coating as well as without Radachlorin
were detected. Efficient nonradiative energy transfer from Tb3+ to the Radachlorin was demonstrated.
The maximum energy transfer coefficients for the nanoparticles conjugated with Radachlorin via
polyvinylpyrrolidone and without the coating were 82% and 55%, respectively. The average distance
between the nanoparticle surface and Radachlorin was R0 = 4.5 nm. The best results for X-ray-induced
cytotoxicity were observed for the NP-PVP-Rch sample at the lowest Rch concentration. In particular,
after X-ray irradiation, the survival of A549 human lung carcinoma cells decreased by ~12%. |
ru_RU |
| dc.language.iso |
ru |
ru_RU |
| dc.subject |
|
ru_RU |
| dc.title |
Photo- and X-ray Induced Cytotoxicity of CeF3-YF3-TbF3 Nanoparticle-Polyvinylpyrrolidone—“Radachlorin” Composites for Combined Photodynamic Therapy |
ru_RU |
| dc.type |
Статьи в зарубежных журналах и сборниках |
ru_RU |
|
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