| Форма представления | Статьи в российских журналах и сборниках |
| Год публикации | 2024 |
| Язык | английский |
|
Бисерова Наталья Михайловна, автор
|
| Библиографическое описание на языке оригинала |
Kolesnikov I.A., Biserova N.M. 2024. Structural mechanisms of protection of parasitic larvae from the host's immune factors in the Triaenophorus nodulosus (Cestoda) – perch system. Moscow University Biological Sciences Bulletin, 2024, Vol. 79, No. 2, pp. 70–77. ? Allerton Press, Inc., 2024. ISSN 0096-3925. DOI: 10.3103/S009639252460087X |
| Аннотация |
Abstract—A structural aspect of the parasite–host interactions in the Triaenophorus nodulosus– European perch system was studied; a number of structural mechanisms involved in the parasite's protective reaction against the host's immune response were identified. Plerocercoids are localized in the liver of the intermediate
fish host. In response to invasion, a parasitic granuloma is formed from the host tissues forming a closed capsule around the parasite. It was demonstrated that the capsule wall is multilayered and consists of several cell types. The outer layer (fibrous) is represented by fibroblasts and connective tissue fibers. The inner layer
is formed by several rows of flattened epithelioid cells tightly adjacent to each other and connected by desmosomes. Individual macrophages exhibiting a phagocytic activity were found on the inner surface of the capsule wall. Structural diversity of the cellular elements of the granuloma wall depends on time elapsed since infection and physiological state of the host. Phagocytosis of apical parts of microtriches and tumuli by granuloma macrophages was described for the first time. Crystal-like structures of unknown origin were also found for
the first time in the capsule cavity. The plerocercoid is located freely in the capsule cavity and has formed hooks that (unlike the intestinal stage) are covered with the tegument cytoplasm. The tegument secretes a thick layer of filamentous matrix, extracellular vesicles, and vacuolized microtriches onto the surface. Terminals
of specialized cells secrete three types of secretory products: secretion of frontal glands, secretion of tumuli, and neurosecretion of cup-shaped terminals. Universal structural adaptations common to all stages of parasite development and specialized ones common to tissue plerocercoids were detected. Vacuolized
microtriches belong to the specialized structures that arise in response to the host immunity. |
| Ключевые слова |
Bothriocephalidea, glands, secretory?excretory products, tegument, parasitic capsule, parasite?host interface |
| Название журнала |
Moscow University Biological Sciences Bulletin
|
| Пожалуйста, используйте этот идентификатор, чтобы цитировать или ссылаться на эту карточку |
https://repository.kpfu.ru/?p_id=306047 |
| Файлы ресурса | |
|
|
Полная запись метаданных  |
| Поле DC |
Значение |
Язык |
| dc.contributor.author |
Бисерова Наталья Михайловна |
ru_RU |
| dc.date.accessioned |
2024-01-01T00:00:00Z |
ru_RU |
| dc.date.available |
2024-01-01T00:00:00Z |
ru_RU |
| dc.date.issued |
2024 |
ru_RU |
| dc.identifier.citation |
Kolesnikov I.A., Biserova N.M. 2024. Structural mechanisms of protection of parasitic larvae from the host's immune factors in the Triaenophorus nodulosus (Cestoda) – perch system. Moscow University Biological Sciences Bulletin, 2024, Vol. 79, No. 2, pp. 70–77. ? Allerton Press, Inc., 2024. ISSN 0096-3925. DOI: 10.3103/S009639252460087X |
ru_RU |
| dc.identifier.uri |
https://repository.kpfu.ru/?p_id=306047 |
ru_RU |
| dc.description.abstract |
Moscow University Biological Sciences Bulletin |
ru_RU |
| dc.description.abstract |
Abstract—A structural aspect of the parasite–host interactions in the Triaenophorus nodulosus– European perch system was studied; a number of structural mechanisms involved in the parasite's protective reaction against the host's immune response were identified. Plerocercoids are localized in the liver of the intermediate
fish host. In response to invasion, a parasitic granuloma is formed from the host tissues forming a closed capsule around the parasite. It was demonstrated that the capsule wall is multilayered and consists of several cell types. The outer layer (fibrous) is represented by fibroblasts and connective tissue fibers. The inner layer
is formed by several rows of flattened epithelioid cells tightly adjacent to each other and connected by desmosomes. Individual macrophages exhibiting a phagocytic activity were found on the inner surface of the capsule wall. Structural diversity of the cellular elements of the granuloma wall depends on time elapsed since infection and physiological state of the host. Phagocytosis of apical parts of microtriches and tumuli by granuloma macrophages was described for the first time. Crystal-like structures of unknown origin were also found for
the first time in the capsule cavity. The plerocercoid is located freely in the capsule cavity and has formed hooks that (unlike the intestinal stage) are covered with the tegument cytoplasm. The tegument secretes a thick layer of filamentous matrix, extracellular vesicles, and vacuolized microtriches onto the surface. Terminals
of specialized cells secrete three types of secretory products: secretion of frontal glands, secretion of tumuli, and neurosecretion of cup-shaped terminals. Universal structural adaptations common to all stages of parasite development and specialized ones common to tissue plerocercoids were detected. Vacuolized
microtriches belong to the specialized structures that arise in response to the host immunity. |
ru_RU |
| dc.language.iso |
ru |
ru_RU |
| dc.subject |
Bothriocephalidea |
ru_RU |
| dc.subject |
glands |
ru_RU |
| dc.subject |
secretory?excretory products |
ru_RU |
| dc.subject |
tegument |
ru_RU |
| dc.subject |
parasitic capsule |
ru_RU |
| dc.subject |
parasite?host interface |
ru_RU |
| dc.title |
Structural mechanisms of protection of parasitic larvae from the host's immune factors in the Triaenophorus nodulosus (Cestoda) – perch system |
ru_RU |
| dc.type |
Статьи в российских журналах и сборниках |
ru_RU |
|
EN 
中文 
ES 
Карта сайта
