КФУ. Карточка публикации. Racemic 2-butanol, 2-ethylhexanol and malic ester in the synthesis of ammonium and hexadecylammonium dithiophosphonates with antimicrobial and cytotoxic activity

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RACEMIC 2-BUTANOL, 2-ETHYLHEXANOL AND MALIC ESTER IN THE SYNTHESIS OF AMMONIUM AND HEXADECYLAMMONIUM DITHIOPHOSPHONATES WITH ANTIMICROBIAL AND CYTOTOXIC ACTIVITY

Форма представления

Статьи в зарубежных журналах и сборниках

Год публикации

2025

Язык

английский

Авторы, сотрудники КФУ

Низамов Ильнар Дамирович, автор

Низамов Ильяс Саидович, автор

Салихов Рамазан Зайтунович, автор

Авторы, аспиранты КФУ

Якимов Владимир Юрьевич, автор

Авторы, студенты КФУ

Калекулин Иван Ильич, автор

Библиографическое описание на языке оригинала

Nizamov, I.S. Racemic 2-butanol, 2-ethylhexanol and malic ester in the synthesis of ammonium and hexadecylammonium dithiophosphonates with antimicrobial and cytotoxic activity / I.S. Nizamov, V.Yu. Yakimov, I.I. Kalekulin, I.D. Nizamov, R.Z. Salikhov, K.A. Ivshin, O.N. Kataeva, G.G. Garifzianova, D.Yu. Grishaev, M.P. Shulaeva, A.A. Parfenov, A.B. Vyshtakalyuk // J. Sulfur Chem. – 2025. – Vol., Is.. – P.1–19. (ISSN: 1741-5993 (Print) 1741-6000 (Online) Journal homepage: www.tandfonline.com/journals/gsrp20) DOI 10.1080/17415993.2025.2551759. WoS, Q3

Аннотация

Dithiophosphonic acids were prepared by the reactions of Lawesson's reagent with racemic 2-butanol, 2-ethylhexanol and diethyl malate reacted with ammonia and hexade- cylamine to form ammonium and hexadecylammonium dithiophosphonates. The molecular structure of ammonium O-(2-butyl)-4-methoxyphenyldithiophosphonate derivative was established by X-ray single crystal analysis. The dithiophosphonic acids obtained and their ammonium salts possessed high hydrolytic stability, antimicrobial activity and low cytotoxicity. The chemical behavior of dithiophosphonic acids and their salts in water and the Mueller-Hinton nutrient broth was established. The electrical conductivity dithiophosphonic acids and their salts in water and in a water–ethanol mixture was studied.

Ключевые слова

Lawessons reagent, ammonia, hexadecylamine, antimicrobial activity, cytotoxicity

Название журнала

Journal of Sulfur Chemistry

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https://repository.kpfu.ru/?p_id=317457

Полная запись метаданных

Поле DC	Значение	Язык
dc.contributor.author	Низамов Ильнар Дамирович	ru_RU
dc.contributor.author	Низамов Ильяс Саидович	ru_RU
dc.contributor.author	Салихов Рамазан Зайтунович	ru_RU
dc.contributor.author	Калекулин Иван Ильич	ru_RU
dc.contributor.author	Якимов Владимир Юрьевич	ru_RU
dc.date.accessioned	2025-01-01T00:00:00Z	ru_RU
dc.date.available	2025-01-01T00:00:00Z	ru_RU
dc.date.issued	2025	ru_RU
dc.identifier.citation	Nizamov, I.S. Racemic 2-butanol, 2-ethylhexanol and malic ester in the synthesis of ammonium and hexadecylammonium dithiophosphonates with antimicrobial and cytotoxic activity / I.S. Nizamov, V.Yu. Yakimov, I.I. Kalekulin, I.D. Nizamov, R.Z. Salikhov, K.A. Ivshin, O.N. Kataeva, G.G. Garifzianova, D.Yu. Grishaev, M.P. Shulaeva, A.A. Parfenov, A.B. Vyshtakalyuk // J. Sulfur Chem. – 2025. – Vol., Is.. – P.1–19. (ISSN: 1741-5993 (Print) 1741-6000 (Online) Journal homepage: www.tandfonline.com/journals/gsrp20) DOI 10.1080/17415993.2025.2551759. WoS, Q3	ru_RU
dc.identifier.uri	https://repository.kpfu.ru/?p_id=317457	ru_RU
dc.description.abstract	Journal of Sulfur Chemistry	ru_RU
dc.description.abstract	Dithiophosphonic acids were prepared by the reactions of Lawesson's reagent with racemic 2-butanol, 2-ethylhexanol and diethyl malate reacted with ammonia and hexade- cylamine to form ammonium and hexadecylammonium dithiophosphonates. The molecular structure of ammonium O-(2-butyl)-4-methoxyphenyldithiophosphonate derivative was established by X-ray single crystal analysis. The dithiophosphonic acids obtained and their ammonium salts possessed high hydrolytic stability, antimicrobial activity and low cytotoxicity. The chemical behavior of dithiophosphonic acids and their salts in water and the Mueller-Hinton nutrient broth was established. The electrical conductivity dithiophosphonic acids and their salts in water and in a water–ethanol mixture was studied.	ru_RU
dc.language.iso	ru	ru_RU
dc.subject	Lawessons reagent	ru_RU
dc.subject	ammonia	ru_RU
dc.subject	hexadecylamine	ru_RU
dc.subject	antimicrobial activity	ru_RU
dc.subject	cytotoxicity	ru_RU
dc.title	Racemic 2-butanol, 2-ethylhexanol and malic ester in the synthesis of ammonium and hexadecylammonium dithiophosphonates with antimicrobial and cytotoxic activity	ru_RU
dc.type	Статьи в зарубежных журналах и сборниках	ru_RU