КФУ. Карточка публикации. In Vivo Kinetics and Biodistribution Analysis of Neoglycoproteins: Effects of Chemically Introduced Glycans on Proteins

КАЗАНСКИЙ
ФЕДЕРАЛЬНЫЙ УНИВЕРСИТЕТ

RUS

- EN
- 中文
- ES

IN VIVO KINETICS AND BIODISTRIBUTION ANALYSIS OF NEOGLYCOPROTEINS: EFFECTS OF CHEMICALLY INTRODUCED GLYCANS ON PROTEINS

Форма представления

Статьи в зарубежных журналах и сборниках

Год публикации

2014

Авторы, сотрудники КФУ

Курбангалиева Альмира Рафаэловна, автор

Другие авторы

A. Ogura

Библиографическое описание на языке оригинала

A. Ogura, A. Kurbangalieva, K. Tanaka. In Vivo Kinetics and Biodistribution Analysis of Neoglycoproteins: Effects of Chemically Introduced Glycans on Proteins // Glycoconj. Journal. 2014. V. 31. № 4. P. 273-279.

Аннотация

Biodistribution and in vivo kinetics analysis of chemically prepared neoglycoproteins are reviewed. Various mono- and oligosaccharides were conjugated onto the protein surface by use of chemical methods. Their kinetic and organ-specific accumulation have extensively been studied after intravenous injection and analyzed by conventional dissection studies, as well as noninvasive methods, such as SPECT, PET, or fluorescence imaging. These studies clearly show the glycan-structure dependency on protein kinetics, which will provide promising possibilities for pharmacological and diagnostic applications.

Ключевые слова

Neoglycoprotein, Bioconjugation, Chemical reaction, N-Glycans, Albumin, In vivo imaging, Tumor targeting, Biodistribution

Название журнала

Glycoconjugate Journal

URL

http://link.springer.com/article/10.1007/s10719-014-9520-3

Пожалуйста, используйте этот идентификатор, чтобы цитировать или ссылаться на эту карточку

https://repository.kpfu.ru/?p_id=86952

Полная запись метаданных

Поле DC	Значение	Язык
dc.contributor.author	Курбангалиева Альмира Рафаэловна	ru_RU
dc.date.accessioned	2014-01-01T00:00:00Z	ru_RU
dc.date.available	2014-01-01T00:00:00Z	ru_RU
dc.date.issued	2014	ru_RU
dc.identifier.citation	A. Ogura, A. Kurbangalieva, K. Tanaka. In Vivo Kinetics and Biodistribution Analysis of Neoglycoproteins: Effects of Chemically Introduced Glycans on Proteins // Glycoconj. Journal. 2014. V. 31. № 4. P. 273-279.	ru_RU
dc.identifier.uri	https://repository.kpfu.ru/?p_id=86952	ru_RU
dc.description.abstract	Glycoconjugate Journal	ru_RU
dc.description.abstract	Biodistribution and in vivo kinetics analysis of chemically prepared neoglycoproteins are reviewed. Various mono- and oligosaccharides were conjugated onto the protein surface by use of chemical methods. Their kinetic and organ-specific accumulation have extensively been studied after intravenous injection and analyzed by conventional dissection studies, as well as noninvasive methods, such as SPECT, PET, or fluorescence imaging. These studies clearly show the glycan-structure dependency on protein kinetics, which will provide promising possibilities for pharmacological and diagnostic applications.	ru_RU
dc.language.iso	ru	ru_RU
dc.subject	Neoglycoprotein	ru_RU
dc.subject	Bioconjugation	ru_RU
dc.subject	Chemical reaction	ru_RU
dc.subject	N-Glycans	ru_RU
dc.subject	Albumin	ru_RU
dc.subject	In vivo imaging	ru_RU
dc.subject	Tumor targeting	ru_RU
dc.subject	Biodistribution	ru_RU
dc.title	In Vivo Kinetics and Biodistribution Analysis of Neoglycoproteins: Effects of Chemically Introduced Glycans on Proteins	ru_RU
dc.type	Статьи в зарубежных журналах и сборниках	ru_RU