КФУ. Карточка публикации. Morpholes neurons compromise the development of cortical connectivity

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MORPHOLES NEURONS COMPROMISE THE DEVELOPMENT OF CORTICAL CONNECTIVITY

Форма представления

Статьи в зарубежных журналах и сборниках

Год публикации

2009

Авторы, сотрудники КФУ

Гафаров Фаиль Мубаракович, автор

Хуснутдинов Наиль Рустамович, автор

Другие авторы

Galimyanov, F.

Библиографическое описание на языке оригинала

Gafarov, F. , Khusnutdinov, N., Galimyanov, F. Morpholes neurons compromise the development of cortical connectivity. Journal of Integrative Neuroscience Volume 8, Issue 1, 2009, Pages 35-48

Аннотация

It is currently accepted that cortical maps are dynamic constructions that are altered in response to external input. Experience-dependent structural changes in cortical microcircuits lead to changes of activity, i.e., changes in information encoded. Specific patterns of external stimulation can lead to creation of new synaptic connections between neurons. The calcium influxes controlled by neuronal activity regulate the processes of neurotrophic factors released by neurons, growth cones movement and synapse differentiation in developing neural systems. We propose a model for description and investigation of the activity dependent development of neural networks. The dynamics of the network parameters (activity, diffusion of axon guidance chemicals, growth cone position) is described by a closed set of differential equations. The model presented here describes the development of neural networks under the assumption of activity dependent axon guidance molecules. Numerical simulation show

Ключевые слова

Axon guidance; Network growth; Structural plasticity

Название журнала

Journal of Integrative Neuroscience

URL

http://www.worldscientific.com/doi/abs/10.1142/S0219635209002058

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https://repository.kpfu.ru/?p_id=89247

Полная запись метаданных

Поле DC	Значение	Язык
dc.contributor.author	Гафаров Фаиль Мубаракович	ru_RU
dc.contributor.author	Хуснутдинов Наиль Рустамович	ru_RU
dc.date.accessioned	2009-01-01T00:00:00Z	ru_RU
dc.date.available	2009-01-01T00:00:00Z	ru_RU
dc.date.issued	2009	ru_RU
dc.identifier.citation	Gafarov, F. , Khusnutdinov, N., Galimyanov, F. Morpholes neurons compromise the development of cortical connectivity. Journal of Integrative Neuroscience Volume 8, Issue 1, 2009, Pages 35-48	ru_RU
dc.identifier.uri	https://repository.kpfu.ru/?p_id=89247	ru_RU
dc.description.abstract	Journal of Integrative Neuroscience	ru_RU
dc.description.abstract	It is currently accepted that cortical maps are dynamic constructions that are altered in response to external input. Experience-dependent structural changes in cortical microcircuits lead to changes of activity, i.e., changes in information encoded. Specific patterns of external stimulation can lead to creation of new synaptic connections between neurons. The calcium influxes controlled by neuronal activity regulate the processes of neurotrophic factors released by neurons, growth cones movement and synapse differentiation in developing neural systems. We propose a model for description and investigation of the activity dependent development of neural networks. The dynamics of the network parameters (activity, diffusion of axon guidance chemicals, growth cone position) is described by a closed set of differential equations. The model presented here describes the development of neural networks under the assumption of activity dependent axon guidance molecules. Numerical simulation show	ru_RU
dc.language.iso	ru	ru_RU
dc.subject		ru_RU
dc.title	Morpholes neurons compromise the development of cortical connectivity	ru_RU
dc.type	Статьи в зарубежных журналах и сборниках	ru_RU