КФУ. Карточка публикации. Evaluation of Cell Membrane-Modulating Properties of Non-Ionic Surfactants With the Use of Atomic Force Spectroscopy

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ФЕДЕРАЛЬНЫЙ УНИВЕРСИТЕТ

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EVALUATION OF CELL MEMBRANE-MODULATING PROPERTIES OF NON-IONIC SURFACTANTS WITH THE USE OF ATOMIC FORCE SPECTROSCOPY

Форма представления

Статьи в зарубежных журналах и сборниках

Год публикации

2014

Язык

русский

Авторы, сотрудники КФУ

Осин Юрий Николаевич, автор

Библиографическое описание на языке оригинала

Оksana V. Bondar, Denis V. Lebedev, Vesta D. Shevchenko, Anastas A. Bukharaev, Yury N. Osin, Yurii G. Shtyrlin, Timur I. Abdullin Evaluation of Cell Membrane-Modulating Properties of Non-Ionic Surfactants With the Use of Atomic Force Spectroscopy // BioNanoSceince, -2014

Аннотация

Analytical possibilities of atomic force spectroscopy (AFS) in liquid were studied upon interaction of membranotropic polymers with the plasma membrane of human cells. Topographical visualization of tightly adherent dermal fibroblasts, but not relatively soft prostate cancer (PC-3) cells, was achieved using a conventional triangular cantilever. A microsphere-based probe has been developed and applied for AFS analysis of micromechanical properties of PC-3 cells. Non-ionic block copolymers of ethylene oxide and propylene oxide, bi-functional Pluronic? L61 and glycerol-based tri-functional copolymer (TFC), were studied as potential modulators of cellular membranes and drug delivery systems [1]. As indicated by dynamic light scattering and fluorescent techniques, Pluronic? L61 and TFC were adsorbed onto the cell surface and inserted into the plasma membrane in different extent.

Ключевые слова

cellular membranes; elastic properties; cancer cells; atomic force spectroscopy; non-ionic surfactants; block copolymers of ethylene oxide and propylene oxide; membrane-modulating properties; microviscosity; nanocarriers

Название журнала

BioNanoScience

URL

http://link.springer.com/journal/12668

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https://repository.kpfu.ru/?p_id=93874

Полная запись метаданных

Поле DC	Значение	Язык
dc.contributor.author	Осин Юрий Николаевич	ru_RU
dc.date.accessioned	2014-01-01T00:00:00Z	ru_RU
dc.date.available	2014-01-01T00:00:00Z	ru_RU
dc.date.issued	2014	ru_RU
dc.identifier.citation	Оksana V. Bondar, Denis V. Lebedev, Vesta D. Shevchenko, Anastas A. Bukharaev, Yury N. Osin, Yurii G. Shtyrlin, Timur I. Abdullin Evaluation of Cell Membrane-Modulating Properties of Non-Ionic Surfactants With the Use of Atomic Force Spectroscopy // BioNanoSceince, -2014	ru_RU
dc.identifier.uri	https://repository.kpfu.ru/?p_id=93874	ru_RU
dc.description.abstract	BioNanoScience	ru_RU
dc.description.abstract	Analytical possibilities of atomic force spectroscopy (AFS) in liquid were studied upon interaction of membranotropic polymers with the plasma membrane of human cells. Topographical visualization of tightly adherent dermal fibroblasts, but not relatively soft prostate cancer (PC-3) cells, was achieved using a conventional triangular cantilever. A microsphere-based probe has been developed and applied for AFS analysis of micromechanical properties of PC-3 cells. Non-ionic block copolymers of ethylene oxide and propylene oxide, bi-functional Pluronic? L61 and glycerol-based tri-functional copolymer (TFC), were studied as potential modulators of cellular membranes and drug delivery systems [1]. As indicated by dynamic light scattering and fluorescent techniques, Pluronic? L61 and TFC were adsorbed onto the cell surface and inserted into the plasma membrane in different extent.	ru_RU
dc.language.iso	ru	ru_RU
dc.subject		ru_RU
dc.title	Evaluation of Cell Membrane-Modulating Properties of Non-Ionic Surfactants With the Use of Atomic Force Spectroscopy	ru_RU
dc.type	Статьи в зарубежных журналах и сборниках	ru_RU