KFU. Card publication. Modulation of defensive reflex conditioning in snails by serotonin

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FEDERAL UNIVERSITY

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MODULATION OF DEFENSIVE REFLEX CONDITIONING IN SNAILS BY SEROTONIN

Form of presentation

Articles in international journals and collections

Year of publication

2015

Язык

английский

Authors, employees of KFU

Andrianov Vyacheslav Vadimovich, author

Bogodvid Tatyana Khalilovna, author

Gaynutdinov Khalil Latypovich, author

Golovchenko Aleksandra Nikolaevna, author

Deryabina Irina Borisovna, author

Muranova Lyudmila Nikolaevna, author

Other authors

Vinarskaya Aliya Khalilovna, author

Tagirova Roza Rishatovna, author

Bibliographic description in the original language

Andrianov V. V. Modulation of defensive reflex conditioning in snails by serotonin / V. V. Andrianov, T. Kh. Bogodvid, I. B. Deryabina, A. N. Golovchenko, L. N. Muranova, R. R. Tagirova, A. Kh. Vinarskaya, Kh. L. Gainutdinov // Front. Behav. Neurosci. - 2015. - V. 9. - Article 279. - P. 1-12.

Annotation

We studied the role of serotonin in the mechanisms of learning in terrestrial snails. To produce a serotonin deficit, the ?neurotoxic? analogues of serotonin, 5,6- or 5,7-dihydroxytryptamine (5,6/5,7-DHT) were used. Injection of 5,6/5,7-DHT was found to disrupt defensive reflex conditioning. Within two weeks of neurotoxin application, the ability to learn had recovered. Daily injection of serotonin before a training session accelerated defensive reflex conditioning and daily injections of 5-HTP in snails with a deficiency of serotonin induced by 5,7-DHT restored the snail?s ability to learn. We discovered that injections of the neurotoxins 5,6/5,7-DHT as well as serotonin, caused a decrease in the resting and threshold potentials of the premotor interneurons LPa3 and RPa3.

Keywords

serotonin, associative learning, identified neuron, membrane potential, threshold potential, snail

The name of the journal

Frontiers in Behavioral Neuroscience

On-line resource for training course

http://dspace.kpfu.ru/xmlui/bitstream/handle/net/32442/Andrianov2015_09_00279.pdf?sequence=1&isAllowed=y

Please use this ID to quote from or refer to the card

https://repository.kpfu.ru/eng/?p_id=118191&p_lang=2

Resource files

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Andrianov2015_09_00279.pdf	1,68	pdf	show / download

Full metadata record

Field DC	Value	Language
dc.contributor.author	Andrianov Vyacheslav Vadimovich	ru_RU
dc.contributor.author	Bogodvid Tatyana Khalilovna	ru_RU
dc.contributor.author	Gaynutdinov Khalil Latypovich	ru_RU
dc.contributor.author	Golovchenko Aleksandra Nikolaevna	ru_RU
dc.contributor.author	Deryabina Irina Borisovna	ru_RU
dc.contributor.author	Muranova Lyudmila Nikolaevna	ru_RU
dc.contributor.author	Vinarskaya Aliya Khalilovna	ru_RU
dc.contributor.author	Tagirova Roza Rishatovna	ru_RU
dc.date.accessioned	2015-01-01T00:00:00Z	ru_RU
dc.date.available	2015-01-01T00:00:00Z	ru_RU
dc.date.issued	2015	ru_RU
dc.identifier.citation	Andrianov V. V. Modulation of defensive reflex conditioning in snails by serotonin / V. V. Andrianov, T. Kh. Bogodvid, I. B. Deryabina, A. N. Golovchenko, L. N. Muranova, R. R. Tagirova, A. Kh. Vinarskaya, Kh. L. Gainutdinov // Front. Behav. Neurosci. - 2015. - V. 9. - Article 279. - P. 1-12.	ru_RU
dc.identifier.uri	https://repository.kpfu.ru/eng/?p_id=118191&p_lang=2	ru_RU
dc.description.abstract	Frontiers in Behavioral Neuroscience	ru_RU
dc.description.abstract	We studied the role of serotonin in the mechanisms of learning in terrestrial snails. To produce a serotonin deficit, the ?neurotoxic? analogues of serotonin, 5,6- or 5,7-dihydroxytryptamine (5,6/5,7-DHT) were used. Injection of 5,6/5,7-DHT was found to disrupt defensive reflex conditioning. Within two weeks of neurotoxin application, the ability to learn had recovered. Daily injection of serotonin before a training session accelerated defensive reflex conditioning and daily injections of 5-HTP in snails with a deficiency of serotonin induced by 5,7-DHT restored the snail?s ability to learn. We discovered that injections of the neurotoxins 5,6/5,7-DHT as well as serotonin, caused a decrease in the resting and threshold potentials of the premotor interneurons LPa3 and RPa3.	ru_RU
dc.language.iso	ru	ru_RU
dc.subject	serotonin	ru_RU
dc.subject	associative learning	ru_RU
dc.subject	identified neuron	ru_RU
dc.subject	membrane potential	ru_RU
dc.subject	threshold potential	ru_RU
dc.subject	snail	ru_RU
dc.title	Modulation of defensive reflex conditioning in snails by serotonin	ru_RU
dc.type	Articles in international journals and collections	ru_RU