KFU. Card publication. p-tert-Butylthiacalix[4]arenes equipped with guanidinium fragments: aggregation, cytotoxicity, and DNA binding abilities?

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P-TERT-BUTYLTHIACALIX[4]ARENES EQUIPPED WITH GUANIDINIUM FRAGMENTS: AGGREGATION, CYTOTOXICITY, AND DNA BINDING ABILITIES?

Form of presentation

Articles in international journals and collections

Year of publication

2016

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Authors, employees of KFU

Osin Yuriy Nikolaevich, author

Other authors

Imatdinov Ilnaz a, author

Bibliographic description in the original language

Andrey Galukhin p-tert-Butylthiacalix[4]arenes equipped with guanidinium fragments: aggregation, cytotoxicity, and DNA binding abilities?/ Andrey Galukhin, Ilnaz Imatdinov and Yuri Osin//The Royal Society of Chemistry, RSC Adv., 2016, 6, 32722–32726

Annotation

Mono-, di- and tetracationic thiacalix[4]arenes in a 1,3-alternate conformation functionalized with guanidinium groups showed a strong dependence of the aggregation properties with the ratio of guanidinium/n-decyl fragments attached to phenolic groups. Increasing the amount of guanidinium fragments improved the macrocycles solubility in water as well as the sorption capacity towards polynucleotide molecules. The synthesized thiacalixarenes showed relatively high toxicity comparable with that for similar receptors based on the classical calixarene.

Keywords

p-tert-Butylthiacalix[4]arenes, guanidinium fragments

The name of the journal

RSC Advances

Please use this ID to quote from or refer to the card

https://repository.kpfu.ru/eng/?p_id=129947&p_lang=2

Resource files

File name	Size (MB)	Format
Galuhin.pdf	0,54	pdf	show / download

Full metadata record

Field DC	Value	Language
dc.contributor.author	Osin Yuriy Nikolaevich	ru_RU
dc.contributor.author	Imatdinov Ilnaz a	ru_RU
dc.date.accessioned	2016-01-01T00:00:00Z	ru_RU
dc.date.available	2016-01-01T00:00:00Z	ru_RU
dc.date.issued	2016	ru_RU
dc.identifier.citation	Andrey Galukhin p-tert-Butylthiacalix[4]arenes equipped with guanidinium fragments: aggregation, cytotoxicity, and DNA binding abilities?/ Andrey Galukhin, Ilnaz Imatdinov and Yuri Osin//The Royal Society of Chemistry, RSC Adv., 2016, 6, 32722–32726	ru_RU
dc.identifier.uri	https://repository.kpfu.ru/eng/?p_id=129947&p_lang=2	ru_RU
dc.description.abstract	RSC Advances	ru_RU
dc.description.abstract	Mono-, di- and tetracationic thiacalix[4]arenes in a 1,3-alternate conformation functionalized with guanidinium groups showed a strong dependence of the aggregation properties with the ratio of guanidinium/n-decyl fragments attached to phenolic groups. Increasing the amount of guanidinium fragments improved the macrocycles solubility in water as well as the sorption capacity towards polynucleotide molecules. The synthesized thiacalixarenes showed relatively high toxicity comparable with that for similar receptors based on the classical calixarene.	ru_RU
dc.language.iso	ru	ru_RU
dc.subject	p-tert-Butylthiacalix[4]arenes	ru_RU
dc.subject	guanidinium fragments	ru_RU
dc.title	p-tert-Butylthiacalix[4]arenes equipped with guanidinium fragments: aggregation, cytotoxicity, and DNA binding abilities?	ru_RU
dc.type	Articles in international journals and collections	ru_RU