KFU. Card publication. Supramolecular chirality in self-assembled peptide amphiphile nanostructures

KAZAN
FEDERAL UNIVERSITY

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SUPRAMOLECULAR CHIRALITY IN SELF-ASSEMBLED PEPTIDE AMPHIPHILE NANOSTRUCTURES

Form of presentation

Articles in international journals and collections

Year of publication

2015

Язык

английский

Authors, employees of KFU

Garifullin Ruslan Ildarovich, author

Bibliographic description in the original language

Garifullin R., Guler M.O., “Supramolecular chirality in self-assembled peptide amphiphile nanostructures”, Chemical Communications, 2015, 51, 12470.

Annotation

Induced supramolecular chirality was investigated in the self-assembled peptide amphiphile (PA) nanosystems. Having shown that peptide chirality can be transferred to the covalently-attached achiral pyrene moiety upon PA self-assembly, the chiral information is transferred to molecular pyrene via weak noncovalent interactions. In the first design of a supramolecular chiral system, the chromophore was covalently attached to a peptide sequence (VVAGH) via an ε-aminohexanoic acid spacer. Covalent attachment yielded a PA molecule self-assembling into nanofibers. In the second design, the chromophore was encapsulated within the hydrophobic core of self-assembled nanofibers of another PA consisting of the same peptide sequence attached to lauric acid. We observed that supramolecular chirality was induced in the chromophore by PA assembly into chiral nanostructures, whether it was covalently attached, or noncovalently bound

Keywords

Self-assembly, peptides, supramolecular chirality

The name of the journal

Chemical Communications

URL

http://pubs.rsc.org/is/content/articlelanding/2015/cc/c5cc04982b#!divAbstract

Please use this ID to quote from or refer to the card

https://repository.kpfu.ru/eng/?p_id=138784&p_lang=2

Full metadata record

Field DC	Value	Language
dc.contributor.author	Garifullin Ruslan Ildarovich	ru_RU
dc.date.accessioned	2015-01-01T00:00:00Z	ru_RU
dc.date.available	2015-01-01T00:00:00Z	ru_RU
dc.date.issued	2015	ru_RU
dc.identifier.citation	Garifullin R., Guler M.O., “Supramolecular chirality in self-assembled peptide amphiphile nanostructures”, Chemical Communications, 2015, 51, 12470.	ru_RU
dc.identifier.uri	https://repository.kpfu.ru/eng/?p_id=138784&p_lang=2	ru_RU
dc.description.abstract	Chemical Communications	ru_RU
dc.description.abstract	Induced supramolecular chirality was investigated in the self-assembled peptide amphiphile (PA) nanosystems. Having shown that peptide chirality can be transferred to the covalently-attached achiral pyrene moiety upon PA self-assembly, the chiral information is transferred to molecular pyrene via weak noncovalent interactions. In the first design of a supramolecular chiral system, the chromophore was covalently attached to a peptide sequence (VVAGH) via an ε-aminohexanoic acid spacer. Covalent attachment yielded a PA molecule self-assembling into nanofibers. In the second design, the chromophore was encapsulated within the hydrophobic core of self-assembled nanofibers of another PA consisting of the same peptide sequence attached to lauric acid. We observed that supramolecular chirality was induced in the chromophore by PA assembly into chiral nanostructures, whether it was covalently attached, or noncovalently bound	ru_RU
dc.language.iso	ru	ru_RU
dc.subject	Self-assembly	ru_RU
dc.subject	peptides	ru_RU
dc.subject	supramolecular chirality	ru_RU
dc.title	Supramolecular chirality in self-assembled peptide amphiphile nanostructures	ru_RU
dc.type	Articles in international journals and collections	ru_RU