KFU. Card publication. Synthesis and antiadrenergic properties of βsubstituted alcohols based on 6-hydroxymethylpyridoxine

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SYNTHESIS AND ANTIADRENERGIC PROPERTIES OF βSUBSTITUTED ALCOHOLS BASED ON 6-HYDROXYMETHYLPYRIDOXINE

Form of presentation

Articles in international journals and collections

Year of publication

2016

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Authors, employees of KFU

Aleksandrova Elvira Grigorevna, author

Ziganshina Liliya Evgenevna, author

Iksanova Alfiya Gabdulakhatovna, author

Koshkin Sergey Alekseevich, author

Lodochnikova Olga Aleksandrovna, author

Mullanurova Aliya Faritovna, author

Pavelev Roman Sergeevich, author

Sitdikova Guzel Faritovna, author

Khaertdinov Nail Nazimovich, author

Khayrullina Regina Rishatovna, author

Shtyrlin Yuriy Grigorevich, author

Bibliographic description in the original language

Pavelyev R. S. Synthesis and antiadrenergic properties of βsubstituted alcohols based on 6-hydroxymethylpyridoxine /R. S. Pavelyev, R. R. Khairullina, S. A. Koshkin, A. G. Iksanova, O. A. Lodochnikova, N. N. Khaertdinov, G. F. Sitdikova, A. F. Safina, E. G. Aleksandrova,a L. E. Ziganshina, Yu. G. Shtyrlin // Russian Chemical Bulletin, International Edition, Vol. 65, No. 2, P. 519—531, February, 2016

Annotation

An approach to the synthesis of epoxides based on 6hydroxymethylpyridoxine acetals was developed. The epoxides obtained were involved in the ring opening reactions by nitrogen, oxygen, and sulfurcontaining nucleophiles. Cytotoxicity and antiadrenergic properties of some synthesized compounds were studied on the models in situ and in vivo.

Keywords

pyridoxine, 6hydroxymethylpyridoxine, epoxides, βsubstituted alcohols, anti adrenergic activity, β-blockers.

The name of the journal

Russian Chemical Bulletin

URL

http://link.springer.com/article/10.1007/s11172-016-1332-0

Please use this ID to quote from or refer to the card

https://repository.kpfu.ru/eng/?p_id=143020&p_lang=2

Resource files

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R.S._Pavelev.pdf	0,33	pdf	show / download

Full metadata record

Field DC	Value	Language
dc.contributor.author	Aleksandrova Elvira Grigorevna	ru_RU
dc.contributor.author	Ziganshina Liliya Evgenevna	ru_RU
dc.contributor.author	Iksanova Alfiya Gabdulakhatovna	ru_RU
dc.contributor.author	Koshkin Sergey Alekseevich	ru_RU
dc.contributor.author	Lodochnikova Olga Aleksandrovna	ru_RU
dc.contributor.author	Mullanurova Aliya Faritovna	ru_RU
dc.contributor.author	Pavelev Roman Sergeevich	ru_RU
dc.contributor.author	Sitdikova Guzel Faritovna	ru_RU
dc.contributor.author	Khaertdinov Nail Nazimovich	ru_RU
dc.contributor.author	Khayrullina Regina Rishatovna	ru_RU
dc.contributor.author	Shtyrlin Yuriy Grigorevich	ru_RU
dc.date.accessioned	2016-01-01T00:00:00Z	ru_RU
dc.date.available	2016-01-01T00:00:00Z	ru_RU
dc.date.issued	2016	ru_RU
dc.identifier.citation	Pavelyev R. S. Synthesis and antiadrenergic properties of βsubstituted alcohols based on 6-hydroxymethylpyridoxine /R. S. Pavelyev, R. R. Khairullina, S. A. Koshkin, A. G. Iksanova, O. A. Lodochnikova, N. N. Khaertdinov, G. F. Sitdikova, A. F. Safina, E. G. Aleksandrova,a L. E. Ziganshina, Yu. G. Shtyrlin // Russian Chemical Bulletin, International Edition, Vol. 65, No. 2, P. 519—531, February, 2016	ru_RU
dc.identifier.uri	https://repository.kpfu.ru/eng/?p_id=143020&p_lang=2	ru_RU
dc.description.abstract	Russian Chemical Bulletin	ru_RU
dc.description.abstract	An approach to the synthesis of epoxides based on 6hydroxymethylpyridoxine acetals was developed. The epoxides obtained were involved in the ring opening reactions by nitrogen, oxygen, and sulfurcontaining nucleophiles. Cytotoxicity and antiadrenergic properties of some synthesized compounds were studied on the models in situ and in vivo.	ru_RU
dc.language.iso	ru	ru_RU
dc.subject	pyridoxine	ru_RU
dc.subject	6hydroxymethylpyridoxine	ru_RU
dc.subject	epoxides	ru_RU
dc.subject	βsubstituted alcohols	ru_RU
dc.subject	anti adrenergic activity	ru_RU
dc.subject	β-blockers.	ru_RU
dc.title	Synthesis and antiadrenergic properties of βsubstituted alcohols based on 6-hydroxymethylpyridoxine	ru_RU
dc.type	Articles in international journals and collections	ru_RU