KFU. Card publication. Yohimbine influence on myocardium contractile activity among newborn rats

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YOHIMBINE INFLUENCE ON MYOCARDIUM CONTRACTILE ACTIVITY AMONG NEWBORN RATS

Form of presentation

Articles in Russian journals and collections

Year of publication

2016

Язык

английский

Authors, employees of KFU

Zaripova Railya Irekovna, author

Zefirov Timur Lvovich, author

Ziyatdinova Nafisa Ilgizovna, author

Kupcova Anna Mikhaylovna, author

Authors, postgraduates KFU

Khisamieva Luiza Irekovna, postgraduate kfu

Bibliographic description in the original language

Kuptsova A.M. Yohimbine influence on myocardium contractile activity among newborn rats /A.M. Kuptsova, R.I. Zaripova, L.I. Hisamieva, R.G. Biktemirova, N.I. Ziyatdinova, T.L. Zefirov // International Journal of Advanced Biotechnology and Research. Vol - 7. Issue - 4. 2016. pp. 1305-1309.

Annotation

Alpha2-adrenergic receptors (α2-AP) are widespread in a man's body, including the cardiovascular system. As Gprotein coupled receptors, they perform different functions in the intracellular mechanism regulation. Despite the fact that the α2-adrenoceptors were discovered in a man's heart, it was not possible to detect receptor within protein level, and the study of α2-adrenoceptors in a man's heart was insufficient. The study of α2-adrenoceptor yohimbine blockade influence on the inotropy of right atrium and right ventricle myocardium among newborn and adult rats was carried out in vitro using the device POWER LAB (AD Instruments, ustralia) by the force sensor MLT 050/D (AD Instruments, Australia). The obtained results indicate the decrease of contraction force of the atrium and ventricle myocardial strips at α2-adrenergic receptor blockade with yohimbine among adult rats. A slight short increase of contraction power in atrium myocardium and the reduction of contraction power in ventri

Keywords

heart, inotropy, alfa2- adrenergic receptors, postnatal ontogenesis

The name of the journal

INTERNATIONAL JOURNAL OF ADVANCED BIOTECHNOLOGY AND RESEARCH

Please use this ID to quote from or refer to the card

https://repository.kpfu.ru/eng/?p_id=144810&p_lang=2

Resource files

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ijabr20167411_Kuptsova.pdf	0,25	pdf	show / download

Full metadata record

Field DC	Value	Language
dc.contributor.author	Zaripova Railya Irekovna	ru_RU
dc.contributor.author	Zefirov Timur Lvovich	ru_RU
dc.contributor.author	Ziyatdinova Nafisa Ilgizovna	ru_RU
dc.contributor.author	Kupcova Anna Mikhaylovna	ru_RU
dc.contributor.author	Khisamieva Luiza Irekovna	ru_RU
dc.date.accessioned	2016-01-01T00:00:00Z	ru_RU
dc.date.available	2016-01-01T00:00:00Z	ru_RU
dc.date.issued	2016	ru_RU
dc.identifier.citation	Kuptsova A.M. Yohimbine influence on myocardium contractile activity among newborn rats /A.M. Kuptsova, R.I. Zaripova, L.I. Hisamieva, R.G. Biktemirova, N.I. Ziyatdinova, T.L. Zefirov // International Journal of Advanced Biotechnology and Research. Vol - 7. Issue - 4. 2016. pp. 1305-1309.	ru_RU
dc.identifier.uri	https://repository.kpfu.ru/eng/?p_id=144810&p_lang=2	ru_RU
dc.description.abstract	INTERNATIONAL JOURNAL OF ADVANCED BIOTECHNOLOGY AND RESEARCH	ru_RU
dc.description.abstract	Alpha2-adrenergic receptors (α2-AP) are widespread in a man's body, including the cardiovascular system. As Gprotein coupled receptors, they perform different functions in the intracellular mechanism regulation. Despite the fact that the α2-adrenoceptors were discovered in a man's heart, it was not possible to detect receptor within protein level, and the study of α2-adrenoceptors in a man's heart was insufficient. The study of α2-adrenoceptor yohimbine blockade influence on the inotropy of right atrium and right ventricle myocardium among newborn and adult rats was carried out in vitro using the device POWER LAB (AD Instruments, ustralia) by the force sensor MLT 050/D (AD Instruments, Australia). The obtained results indicate the decrease of contraction force of the atrium and ventricle myocardial strips at α2-adrenergic receptor blockade with yohimbine among adult rats. A slight short increase of contraction power in atrium myocardium and the reduction of contraction power in ventri	ru_RU
dc.language.iso	ru	ru_RU
dc.subject	heart	ru_RU
dc.subject	inotropy	ru_RU
dc.subject	alfa2- adrenergic receptors	ru_RU
dc.subject	postnatal ontogenesis	ru_RU
dc.title	Yohimbine influence on myocardium contractile activity among newborn rats	ru_RU
dc.type	Articles in Russian journals and collections	ru_RU