KFU. Card publication. Photoditazine photodynamic effect on DNA and blood cells of Brachydanio rerio

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FEDERAL UNIVERSITY

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PHOTODITAZINE PHOTODYNAMIC EFFECT ON DNA AND BLOOD CELLS OF BRACHYDANIO RERIO

Form of presentation

Articles in international journals and collections

Year of publication

2017

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Authors, employees of KFU

Leontev Vyacheslav Vitalevich, author

Other authors

Omelchuk Nadezhda Nikolaevna, author

Purckhvanidze Violetta Aleksandrovna, author

Simakov Yuriy Georgievich, author

Talismanov Vladimir Sergeevich, author

Bibliographic description in the original language

Photoditazine photodynamic effect on DNA and blood cells of Brachydanio rerio / V.A. Purtskhvanidze, Y.G. Simakov, N.N. Omelchuk, V.S. Talismanov, V.V. Leontyev // Journal of Pharmaceutical Sciences and Research. - 2017. – Vol. 9(7). - P. 1250-1254.

Annotation

The study is aimed at identifying the morphological and cytogenetic changes in erythrocytes of Brachydanio rerio, arising under the influence of photodynamic effects that models laser modification of blood, with the use of Fotoditazin, a photosensitizer of the chlorine range, and red laser radiation. (Methods of Research) For 15 days, juvenile fish Brachydanio rerio were kept in settled tap water after providing model of laser modification of the blood using Fotoditazin and exposure to laser radiation with the wavelength of 630 nm. The impact on the structure of DNA in the nuclei of red blood cells of Fotoditazin, laser radiation and combined effects of these factors on the changes in the fluorescence spectra of DNA and the color of fluorescence were studied.(Generalization of results and their meaning). It had been shown that separate effects of laser or Fotoditazin did not cause changes in the fluorescence of nuclei of erythrocytes, when the preparations were studied with the use of

Keywords

Fotoditazin, laser radiation, fish erythrocytes? nuclei, acridine orange, nuclei fluorescence, changes in the DNA structure, nuclei polymorphism

The name of the journal

Journal of Pharmaceutical Sciences and Research

On-line resource for training course

http://dspace.kpfu.ru/xmlui/bitstream/handle/net/117256/F_jpsr09071746.pdf?sequence=1&isAllowed=y

URL

http://www.jpsr.pharmainfo.in/issue.php?page=95#

Please use this ID to quote from or refer to the card

https://repository.kpfu.ru/eng/?p_id=166451&p_lang=2

Resource files

File name	Size (MB)	Format
F_jpsr09071746.pdf	1,41	pdf	show / download

Full metadata record

Field DC	Value	Language
dc.contributor.author	Leontev Vyacheslav Vitalevich	ru_RU
dc.contributor.author	Omelchuk Nadezhda Nikolaevna	ru_RU
dc.contributor.author	Purckhvanidze Violetta Aleksandrovna	ru_RU
dc.contributor.author	Simakov Yuriy Georgievich	ru_RU
dc.contributor.author	Talismanov Vladimir Sergeevich	ru_RU
dc.date.accessioned	2017-01-01T00:00:00Z	ru_RU
dc.date.available	2017-01-01T00:00:00Z	ru_RU
dc.date.issued	2017	ru_RU
dc.identifier.citation	Photoditazine photodynamic effect on DNA and blood cells of Brachydanio rerio / V.A. Purtskhvanidze, Y.G. Simakov, N.N. Omelchuk, V.S. Talismanov, V.V. Leontyev // Journal of Pharmaceutical Sciences and Research. - 2017. – Vol. 9(7). - P. 1250-1254.	ru_RU
dc.identifier.uri	https://repository.kpfu.ru/eng/?p_id=166451&p_lang=2	ru_RU
dc.description.abstract	Journal of Pharmaceutical Sciences and Research	ru_RU
dc.description.abstract	The study is aimed at identifying the morphological and cytogenetic changes in erythrocytes of Brachydanio rerio, arising under the influence of photodynamic effects that models laser modification of blood, with the use of Fotoditazin, a photosensitizer of the chlorine range, and red laser radiation. (Methods of Research) For 15 days, juvenile fish Brachydanio rerio were kept in settled tap water after providing model of laser modification of the blood using Fotoditazin and exposure to laser radiation with the wavelength of 630 nm. The impact on the structure of DNA in the nuclei of red blood cells of Fotoditazin, laser radiation and combined effects of these factors on the changes in the fluorescence spectra of DNA and the color of fluorescence were studied.(Generalization of results and their meaning). It had been shown that separate effects of laser or Fotoditazin did not cause changes in the fluorescence of nuclei of erythrocytes, when the preparations were studied with the use of	ru_RU
dc.language.iso	ru	ru_RU
dc.subject	Fotoditazin	ru_RU
dc.subject	laser radiation	ru_RU
dc.subject	fish erythrocytes? nuclei	ru_RU
dc.subject	acridine orange	ru_RU
dc.subject	nuclei fluorescence	ru_RU
dc.subject	changes in the DNA structure	ru_RU
dc.subject	nuclei polymorphism	ru_RU
dc.title	Photoditazine photodynamic effect on DNA and blood cells of Brachydanio rerio	ru_RU
dc.type	Articles in international journals and collections	ru_RU