KFU. Card publication. Gamma-irradiated bifidobacteria establish a protective effect on mice to experimental radiation exposure

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FEDERAL UNIVERSITY

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GAMMA-IRRADIATED BIFIDOBACTERIA ESTABLISH A PROTECTIVE EFFECT ON MICE TO EXPERIMENTAL RADIATION EXPOSURE

Form of presentation

Articles in international journals and collections

Year of publication

2018

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Authors, employees of KFU

Aleksandrova Natalya Mikhaylovna, author

Mukminov Malik Nilovich, author

Shuralev Eduard Arkadevich, author

Other authors

Galimzyanov I. G., author

Khaertynov K. S., author

Khafizov A. S., author

Koshpaeva E. S., author

Medetkhanov F. A., author

Nizamov R. N., author

Sychev K. V., author

Bibliographic description in the original language

Sychev K.V., Nizamov R.N., Mukminov M.N., Khaertynov K.S., Aleksandrova N.M., Galimzyanov I.G., Medetkhanov F.A., Koshpaeva E.S., Khafizov A.S., Shuralev E.A. Gamma-irradiated bifidobacteria establish a protective effect on mice to experimental radiation exposure // BioNanoScience. - 2018. - Vol.8, Is.1. - P.323-328. doi.org/10.1007/s12668-017-0471-6

Annotation

The purpose of this work is to assess the radioprotective effect exerted by the irradiated form of Bifidobacterium bifidum probiotic on experimentally irradiated mice. As a result of the research, we were able to determine experimentally the optimal dose of gamma rays (12–14 Gy) that ensures a switching of the metabolism of probiotic microorganisms towards the synthesis of superoxide dismutase (an antiradical enzyme) and activates production of interferon (a mediator of immunopoiesis) by immunocompetent cells.

Keywords

Bifidobacterium bifidum, gamma radiation, acute radiation syndrome, interferon, superoxide dismutase

The name of the journal

BioNanoScience

URL

https://www.scopus.com/inward/record.uri?eid=2-s2.0-85044395514&doi=10.1007%2fs12668-017-0471-6&partnerID=40&md5=098d323d6c659fc7f5bcd73d6d127bb6

Please use this ID to quote from or refer to the card

https://repository.kpfu.ru/eng/?p_id=179440&p_lang=2

Resource files

File name	Size (MB)	Format
F_Sychev_Bifidobacteria_2018.pdf	0,62	pdf	show / download

Full metadata record

Field DC	Value	Language
dc.contributor.author	Aleksandrova Natalya Mikhaylovna	ru_RU
dc.contributor.author	Mukminov Malik Nilovich	ru_RU
dc.contributor.author	Shuralev Eduard Arkadevich	ru_RU
dc.contributor.author	Galimzyanov I. G.	ru_RU
dc.contributor.author	Khaertynov K. S.	ru_RU
dc.contributor.author	Khafizov A. S.	ru_RU
dc.contributor.author	Koshpaeva E. S.	ru_RU
dc.contributor.author	Medetkhanov F. A.	ru_RU
dc.contributor.author	Nizamov R. N.	ru_RU
dc.contributor.author	Sychev K. V.	ru_RU
dc.date.accessioned	2018-01-01T00:00:00Z	ru_RU
dc.date.available	2018-01-01T00:00:00Z	ru_RU
dc.date.issued	2018	ru_RU
dc.identifier.citation	Sychev K.V., Nizamov R.N., Mukminov M.N., Khaertynov K.S., Aleksandrova N.M., Galimzyanov I.G., Medetkhanov F.A., Koshpaeva E.S., Khafizov A.S., Shuralev E.A. Gamma-irradiated bifidobacteria establish a protective effect on mice to experimental radiation exposure // BioNanoScience. - 2018. - Vol.8, Is.1. - P.323-328. doi.org/10.1007/s12668-017-0471-6	ru_RU
dc.identifier.uri	https://repository.kpfu.ru/eng/?p_id=179440&p_lang=2	ru_RU
dc.description.abstract	BioNanoScience	ru_RU
dc.description.abstract	The purpose of this work is to assess the radioprotective effect exerted by the irradiated form of Bifidobacterium bifidum probiotic on experimentally irradiated mice. As a result of the research, we were able to determine experimentally the optimal dose of gamma rays (12–14 Gy) that ensures a switching of the metabolism of probiotic microorganisms towards the synthesis of superoxide dismutase (an antiradical enzyme) and activates production of interferon (a mediator of immunopoiesis) by immunocompetent cells.	ru_RU
dc.language.iso	ru	ru_RU
dc.subject	Bifidobacterium bifidum	ru_RU
dc.subject	gamma radiation	ru_RU
dc.subject	acute radiation syndrome	ru_RU
dc.subject	interferon	ru_RU
dc.subject	superoxide dismutase	ru_RU
dc.title	Gamma-irradiated bifidobacteria establish a protective effect on mice to experimental radiation exposure	ru_RU
dc.type	Articles in international journals and collections	ru_RU