KFU. Card publication. Isatin derivatives bearing a fluorine atom. Part 1: Synthesis, hemotoxicity and antimicrobial activity evaluation of fluoro-benzylated water-soluble pyridinium isatin-3-acylhydrazones.

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ISATIN DERIVATIVES BEARING A FLUORINE ATOM. PART 1: SYNTHESIS, HEMOTOXICITY AND ANTIMICROBIAL ACTIVITY EVALUATION OF FLUORO-BENZYLATED WATER-SOLUBLE PYRIDINIUM ISATIN-3-ACYLHYDRAZONES.

Form of presentation

Articles in international journals and collections

Year of publication

2019

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Authors, employees of KFU

Bogdanov Andrey Vladimirovich, author

Mironov Vladimir Fedorovich, author

Bibliographic description in the original language

A.V.Bogdanov, I.F.Zaripova, A.D.Voloshina., A.S.Sapunova, N.V.Kulik, I.V. Tsivunina, A.B.Dobrynin, V.F.Mironov. Isatin derivatives bearing a fluorine atom. Part 1: Synthesis, hemotoxicity and antimicrobial activity evaluation of fluoro-benzylated water-soluble pyridinium isatin-3-acylhydrazones. // J. Fluor. Chem. 2019, 227, 109345. Doi 10.1016/j.jfluchem.2019.109345.

Annotation

Elsevier B.V.

Keywords

pyridinium isatin-3-acylhydrazones, antimicrobial activity,

The name of the journal

Elsevier B.V.

URL

https://doi.org/10.1016/j.jfluchem.2019.109345

Please use this ID to quote from or refer to the card

https://repository.kpfu.ru/eng/?p_id=215428&p_lang=2

Full metadata record

Field DC	Value	Language
dc.contributor.author	Bogdanov Andrey Vladimirovich	ru_RU
dc.contributor.author	Mironov Vladimir Fedorovich	ru_RU
dc.date.accessioned	2019-01-01T00:00:00Z	ru_RU
dc.date.available	2019-01-01T00:00:00Z	ru_RU
dc.date.issued	2019	ru_RU
dc.identifier.citation	A.V.Bogdanov, I.F.Zaripova, A.D.Voloshina., A.S.Sapunova, N.V.Kulik, I.V. Tsivunina, A.B.Dobrynin, V.F.Mironov. Isatin derivatives bearing a fluorine atom. Part 1: Synthesis, hemotoxicity and antimicrobial activity evaluation of fluoro-benzylated water-soluble pyridinium isatin-3-acylhydrazones. // J. Fluor. Chem. 2019, 227, 109345. Doi 10.1016/j.jfluchem.2019.109345.	ru_RU
dc.identifier.uri	https://repository.kpfu.ru/eng/?p_id=215428&p_lang=2	ru_RU
dc.description.abstract	Elsevier B.V.	ru_RU
dc.description.abstract	A series of 1-fluorobenzylated isatins and water-soluble pyridinium isatin-3-acylhydrazones on their base were obtained. The biological evaluation of novel hydrazones showed a significant dependence of their antimicrobial activity on the position of fluorine atom in benzyl substituent. The best activity showed compounds containing a 2-fluoro-6-chlorobenzyl fragment with selective action against S. aureus. The absence of hemotoxicity of both fluorine-containing products and their some non-fluorinated analogues was shown.	ru_RU
dc.language.iso	ru	ru_RU
dc.subject	pyridinium isatin-3-acylhydrazones	ru_RU
dc.subject	antimicrobial activity	ru_RU
dc.subject		ru_RU
dc.title	Isatin derivatives bearing a fluorine atom. Part 1: Synthesis, hemotoxicity and antimicrobial activity evaluation of fluoro-benzylated water-soluble pyridinium isatin-3-acylhydrazones.	ru_RU
dc.type	Articles in international journals and collections	ru_RU