KFU. Card publication. АНТИБИОТИКОРЕЗИСТЕНТНОСТЬ STAPHYLOCOCCUS AUREUS И PSEUDOMONAS AERUGINOSA НА МОДЕЛИ МУКОВИСЦИДОЗА КАК ХРОНИЧЕСКОГО ЗАБОЛЕВАНИЯ БРОНХОЛЕГОЧНОЙ СИСТЕМЫ

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АНТИБИОТИКОРЕЗИСТЕНТНОСТЬ STAPHYLOCOCCUS AUREUS И PSEUDOMONAS AERUGINOSA НА МОДЕЛИ МУКОВИСЦИДОЗА КАК ХРОНИЧЕСКОГО ЗАБОЛЕВАНИЯ БРОНХОЛЕГОЧНОЙ СИСТЕМЫ

Form of presentation

Articles in Russian journals and collections

Year of publication

2018

Язык

русский

Authors, employees of KFU

Kadyrova Elvira Rafikovna, author

Bibliographic description in the original language

ANTIBIOTIKOREZISTENTNOST STAPHYLOCOCCUS AUREUS I PSEUDOMONAS AERUGINOSA NA MODELI MUKOVISCIDOZA KAK KhRONIChESKOGO ZABOLEVANIYa BRONKhOLEGOChNOY SISTEMY ? Source: Pediatriya named after G. N. Speransky . mar/apr2018, Vol. 97 Issue 2, p176-186. 11p. ? Author(s): Zakirov, I. I.; Kadyrova, E. R.; Safina, A. I.; Kayumov, A. R

Annotation

The course and prognosis of cystic fibrosis (CF) in many ways depend on the degree of bronchopulmonary system lesion. Important role in the development of chronic inflammation in the bronchopulmonary system belongs to conditionally pathogenic microorganisms. Rational antibiotic therapy (ABT) allows to restrain the natural course of the disease. How ever, wide spread use of antibiotics (AB) creates problems of microorganisms' resistance. The article reviews the literature on antibacterial resistance (ABR) development mechanisms of Staphylococcus aureus and Pseudomonas aeruginosa, which most often colonize the respiratory tract in CF. Staphylococcus aureus and Pseudomonas aeruginosa ABR realizes by the mechanisms of natural and acquired resistance. The acquired resistance of bacteria develops as a result of natural selection through random mutations and/or through the action of antibacterial drugs. Microorganisms carry genetic information of resistance to antibiotics by horizontal gene transfer, which threatens the spread of multidrug resistant bacteria strains. Rational ABT is a key mechanism for restraining the development of bacteria antibiotic resistance.

Keywords

STAPHYLOCOCCUS AUREUS, PSEUDOMONAS AERUGINOSA, МУКОВИСЦИДОЗ, CYSTIC FIBROSIS, АНТИБАКТЕРИАЛЬНАЯ РЕЗИСТЕНТНОСТЬ, ANTIBACTERIAL RESISTANCE

The name of the journal

Педиатрия. Журнал им. Г.Н. Сперанского

Please use this ID to quote from or refer to the card

https://repository.kpfu.ru/eng/?p_id=216394&p_lang=2

Full metadata record

Field DC	Value	Language
dc.contributor.author	Kadyrova Elvira Rafikovna	ru_RU
dc.date.accessioned	2018-01-01T00:00:00Z	ru_RU
dc.date.available	2018-01-01T00:00:00Z	ru_RU
dc.date.issued	2018	ru_RU
dc.identifier.citation	АНТИБИОТИКОРЕЗИСТЕНТНОСТЬ STAPHYLOCOCCUS AUREUS И PSEUDOMONAS AERUGINOSA НА МОДЕЛИ МУКОВИСЦИДОЗА КАК ХРОНИЧЕСКОГО ЗАБОЛЕВАНИЯ БРОНХОЛЕГОЧНОЙ СИСТЕМЫ ? Source: Pediatriya named after G. N. Speransky . mar/apr2018, Vol. 97 Issue 2, p176-186. 11p. ? Author(s): Закиров, И. И.; Кадырова, Э. Р.; Сафина, А. И.; Каюмов, А. Р	ru_RU
dc.identifier.uri	https://repository.kpfu.ru/eng/?p_id=216394&p_lang=2	ru_RU
dc.description.abstract	Педиатрия. Журнал им. Г.Н. Сперанского	ru_RU
dc.description.abstract	The course and prognosis of cystic fibrosis (CF) in many ways depend on the degree of bronchopulmonary system lesion. Important role in the development of chronic inflammation in the bronchopulmonary system belongs to conditionally pathogenic microorganisms. Rational antibiotic therapy (ABT) allows to restrain the natural course of the disease. How ever, wide spread use of antibiotics (AB) creates problems of microorganisms' resistance. The article reviews the literature on antibacterial resistance (ABR) development mechanisms of Staphylococcus aureus and Pseudomonas aeruginosa, which most often colonize the respiratory tract in CF. Staphylococcus aureus and Pseudomonas aeruginosa ABR realizes by the mechanisms of natural and acquired resistance. The acquired resistance of bacteria develops as a result of natural selection through random mutations and/or through the action of antibacterial drugs. Microorganisms carry genetic information of resistance to antibiotics by horizontal gene transfer, which threatens the spread of multidrug resistant bacteria strains. Rational ABT is a key mechanism for restraining the development of bacteria antibiotic resistance.	ru_RU
dc.language.iso	ru	ru_RU
dc.subject	STAPHYLOCOCCUS AUREUS	ru_RU
dc.subject	PSEUDOMONAS AERUGINOSA	ru_RU
dc.subject	МУКОВИСЦИДОЗ	ru_RU
dc.subject	CYSTIC FIBROSIS	ru_RU
dc.subject	АНТИБАКТЕРИАЛЬНАЯ РЕЗИСТЕНТНОСТЬ	ru_RU
dc.subject	ANTIBACTERIAL RESISTANCE	ru_RU
dc.title	АНТИБИОТИКОРЕЗИСТЕНТНОСТЬ STAPHYLOCOCCUS AUREUS И PSEUDOMONAS AERUGINOSA НА МОДЕЛИ МУКОВИСЦИДОЗА КАК ХРОНИЧЕСКОГО ЗАБОЛЕВАНИЯ БРОНХОЛЕГОЧНОЙ СИСТЕМЫ	ru_RU
dc.type	Articles in Russian journals and collections	ru_RU