KFU. Card publication. Multiplex analysis of the activation of the immune system after transection of the rat?s sciatic nerve

KAZAN
FEDERAL UNIVERSITY

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MULTIPLEX ANALYSIS OF THE ACTIVATION OF THE IMMUNE SYSTEM AFTER TRANSECTION OF THE RAT?S SCIATIC NERVE

Form of presentation

Articles in international journals and collections

Year of publication

2016

Authors, employees of KFU

Karimova Adelya Faritovna, author

Masgutov Ruslan Faridovich, author

Masgutova Galina Andreevna, author

Rizvanov Albert Anatolevich, author

Khaybullina Svetlana Francevna, author

Authors, students KFU

Mukhametova Liliya Ramzovna, author

Bibliographic description in the original language

In this study using the model of sciatic nerve transection in rats the cytokine profile of peripheral blood serum and rat sciatic nerve fragments were measured 3, 7 and 14 days after the injury. Histological analysis of sciatic nerve longitudinal sections was carried out at the same periods of time. The cytokine profile of peripheral blood serum of an intact rat as well as the cytokine profile of an intact homogenized sciatic nerve of a rat was examined. Comparative study of changes in quantitative measures before and after the injury was carried out. It was shown that in peripheral blood serum after the sciatic nerve transection there was a change in quantitative measures of IL-1a, Leptin, IL6, MCP1, MIP-2. In the samples of the rat sciatic nerve the changes were found in the levels of EGF, Fractalkine, G-CSF, IFNg, IL10, IL17A, IL18, IL2, IL6, IP10, Leptin, LIX, MCP1, MIP-1a, MIP-2, RANTES.

Please use this ID to quote from or refer to the card

https://repository.kpfu.ru/eng/?p_id=237252&p_lang=2

Full metadata record

Field DC	Value	Language
dc.contributor.author	Karimova Adelya Faritovna	ru_RU
dc.contributor.author	Masgutov Ruslan Faridovich	ru_RU
dc.contributor.author	Masgutova Galina Andreevna	ru_RU
dc.contributor.author	Rizvanov Albert Anatolevich	ru_RU
dc.contributor.author	Khaybullina Svetlana Francevna	ru_RU
dc.contributor.author	Mukhametova Liliya Ramzovna	ru_RU
dc.date.accessioned	2016-01-01T00:00:00Z	ru_RU
dc.date.available	2016-01-01T00:00:00Z	ru_RU
dc.date.issued	2016	ru_RU
dc.identifier.citation	In this study using the model of sciatic nerve transection in rats the cytokine profile of peripheral blood serum and rat sciatic nerve fragments were measured 3, 7 and 14 days after the injury. Histological analysis of sciatic nerve longitudinal sections was carried out at the same periods of time. The cytokine profile of peripheral blood serum of an intact rat as well as the cytokine profile of an intact homogenized sciatic nerve of a rat was examined. Comparative study of changes in quantitative measures before and after the injury was carried out. It was shown that in peripheral blood serum after the sciatic nerve transection there was a change in quantitative measures of IL-1a, Leptin, IL6, MCP1, MIP-2. In the samples of the rat sciatic nerve the changes were found in the levels of EGF, Fractalkine, G-CSF, IFNg, IL10, IL17A, IL18, IL2, IL6, IP10, Leptin, LIX, MCP1, MIP-1a, MIP-2, RANTES.	ru_RU
dc.identifier.uri	https://repository.kpfu.ru/eng/?p_id=237252&p_lang=2	ru_RU
dc.language.iso	ru	ru_RU
dc.title	Multiplex analysis of the activation of the immune system after transection of the rat?s sciatic nerve	ru_RU
dc.type	Articles in international journals and collections	ru_RU