KFU. Card publication. The Effects of Repeated Administration of the Micellar Complex of Methylprednisolone on the Locomotor Activity of a Terrestrial Snails

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THE EFFECTS OF REPEATED ADMINISTRATION OF THE MICELLAR COMPLEX OF METHYLPREDNISOLONE ON THE LOCOMOTOR ACTIVITY OF A TERRESTRIAL SNAILS

Form of presentation

Articles in international journals and collections

Year of publication

2020

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Authors, employees of KFU

Andrianov Vyacheslav Vadimovich, author

Baltin Maksim Eduardovich, author

Gaynutdinov Khalil Latypovich, author

Deryabina Irina Borisovna, author

Kamalov Marat Ilyasovich, author

Moiseeva Marina Vladimirovna, author

Silanteva Dinara Irekovna, author

Bibliographic description in the original language

Silant'eva, D.I., Deryabina, I.B., Baltin, M.E. et al. The Effects of Repeated Administration of the Micellar Complex of Methylprednisolone on the Locomotor Activity of a Terrestrial Snails. Bull Exp Biol Med. 2020. Vol. 170, No. 1, P. 5-9. https://doi.org/10.1007/s10517-020-04993-5

Annotation

We studied the effects of repeated injections of methylprednisolone and its micellar complex with block-copolymer on locomotor activity of a terrestrial snail. It was shown that methylprednisolone solution injected into the hemolymph of the animal produced a direct effect on the muscle system of the animal as soon as 1 h after administration: it slowed down snail locomotion and reduced contractile activity of the foot muscles. The micellar complex of methylprednisolone with block-copolymer prevented this effect during the first 2 days of injection and negatively affected locomotion only in 2 days after injection, the decrease in locomotion in this case was not accompanied by a decrease in contractile activity of the foot muscle

Keywords

methylprednisolone; amphiphilic trifunctional block-copolymer; snail; locomotion; contractile activity of the muscles of the mollusk sole

The name of the journal

Bulletin of Experimental Biology and Medicine

URL

https://link.springer.com/article/10.1007/s10517-020-04993-5

Please use this ID to quote from or refer to the card

https://repository.kpfu.ru/eng/?p_id=242352&p_lang=2

Resource files

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SilantEva2020_Article_TheEffectsOfRepeatedAdministra.pdf	0,41	pdf	show / download

Full metadata record

Field DC	Value	Language
dc.contributor.author	Andrianov Vyacheslav Vadimovich	ru_RU
dc.contributor.author	Baltin Maksim Eduardovich	ru_RU
dc.contributor.author	Gaynutdinov Khalil Latypovich	ru_RU
dc.contributor.author	Deryabina Irina Borisovna	ru_RU
dc.contributor.author	Kamalov Marat Ilyasovich	ru_RU
dc.contributor.author	Moiseeva Marina Vladimirovna	ru_RU
dc.contributor.author	Silanteva Dinara Irekovna	ru_RU
dc.date.accessioned	2020-01-01T00:00:00Z	ru_RU
dc.date.available	2020-01-01T00:00:00Z	ru_RU
dc.date.issued	2020	ru_RU
dc.identifier.citation	Silant'eva, D.I., Deryabina, I.B., Baltin, M.E. et al. The Effects of Repeated Administration of the Micellar Complex of Methylprednisolone on the Locomotor Activity of a Terrestrial Snails. Bull Exp Biol Med. 2020. Vol. 170, No. 1, P. 5-9. https://doi.org/10.1007/s10517-020-04993-5	ru_RU
dc.identifier.uri	https://repository.kpfu.ru/eng/?p_id=242352&p_lang=2	ru_RU
dc.description.abstract	Bulletin of Experimental Biology and Medicine	ru_RU
dc.description.abstract	We studied the effects of repeated injections of methylprednisolone and its micellar complex with block-copolymer on locomotor activity of a terrestrial snail. It was shown that methylprednisolone solution injected into the hemolymph of the animal produced a direct effect on the muscle system of the animal as soon as 1 h after administration: it slowed down snail locomotion and reduced contractile activity of the foot muscles. The micellar complex of methylprednisolone with block-copolymer prevented this effect during the first 2 days of injection and negatively affected locomotion only in 2 days after injection, the decrease in locomotion in this case was not accompanied by a decrease in contractile activity of the foot muscle	ru_RU
dc.language.iso	ru	ru_RU
dc.subject		ru_RU
dc.title	The Effects of Repeated Administration of the Micellar Complex of Methylprednisolone on the Locomotor Activity of a Terrestrial Snails	ru_RU
dc.type	Articles in international journals and collections	ru_RU