KFU. Card publication. Hematologic features of children and adolescent patients with acute hypersensitivity reactions on drugs and food

KAZAN
FEDERAL UNIVERSITY

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HEMATOLOGIC FEATURES OF CHILDREN AND ADOLESCENT PATIENTS WITH ACUTE HYPERSENSITIVITY REACTIONS ON DRUGS AND FOOD

Form of presentation

Articles in international journals and collections

Year of publication

2020

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Authors, employees of KFU

Kubysheva Nailya Iskhakovna, author

Other authors

Balabolkin Ivan , author

Bulgakova Vilya , author

Eliseeva Tatyana , author

Geppe Natalia , author

Ignatov Stanislav , author

Khaletskaya Olga , author

Ovsyannikov Dmitry , author

Podchernyaeva Nadezhda , author

Trushanina Polina , author

Tush Elena , author

Bibliographic description in the original language

Eliseeva, T. I., Balabolkin, I. I., Geppe, N. A., Tush, E. V., Ovsyannikov, D. Y., Podchernyaeva, N. S., ... & Khaletskaya, O. V. (2020). Hematologic Features of Children and Adolescent Patients with Acute Hypersensitivity Reactions on Drugs and Food. BioMed Research International, 2020.

Annotation

BioMed Research International

Keywords

Children, acute hypersensitivity, food,

The name of the journal

BioMed Research International

URL

https://www.hindawi.com/journals/bmri/2020/5104284/

Please use this ID to quote from or refer to the card

https://repository.kpfu.ru/eng/?p_id=244244&p_lang=2

Resource files

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F__ematologic_features_of_children_and_adolescent_patients_with_acute_hypersensitivity_reactions_on_drugs_and_food.pdf	1,19	pdf	show / download

Full metadata record

Field DC	Value	Language
dc.contributor.author	Kubysheva Nailya Iskhakovna	ru_RU
dc.contributor.author	Balabolkin Ivan	ru_RU
dc.contributor.author	Bulgakova Vilya	ru_RU
dc.contributor.author	Eliseeva Tatyana	ru_RU
dc.contributor.author	Geppe Natalia	ru_RU
dc.contributor.author	Ignatov Stanislav	ru_RU
dc.contributor.author	Khaletskaya Olga	ru_RU
dc.contributor.author	Ovsyannikov Dmitry	ru_RU
dc.contributor.author	Podchernyaeva Nadezhda	ru_RU
dc.contributor.author	Trushanina Polina	ru_RU
dc.contributor.author	Tush Elena	ru_RU
dc.date.accessioned	2020-01-01T00:00:00Z	ru_RU
dc.date.available	2020-01-01T00:00:00Z	ru_RU
dc.date.issued	2020	ru_RU
dc.identifier.citation	Eliseeva, T. I., Balabolkin, I. I., Geppe, N. A., Tush, E. V., Ovsyannikov, D. Y., Podchernyaeva, N. S., ... & Khaletskaya, O. V. (2020). Hematologic Features of Children and Adolescent Patients with Acute Hypersensitivity Reactions on Drugs and Food. BioMed Research International, 2020.	ru_RU
dc.identifier.uri	https://repository.kpfu.ru/eng/?p_id=244244&p_lang=2	ru_RU
dc.description.abstract	BioMed Research International	ru_RU
dc.description.abstract	Hematological parameters and blood biochemical markers were measured in 131 children and adolescent patients (70 boys) aged 2 to 17 years with acute hypersensitivity reactions induced by food (59 patients) and medicines (72 patients) in order to establish differences in clinical manifestations and hematological parameters in children with food and drug hypersensitivity and to elaborate the hematological criteria for differentiating the possible pathophysiological mechanisms of various types of hypersensitivity. Both groups of patients had comparable clinical symptoms with a predominance of skin lesions. The significant differences between the groups with drug- and food-induced hypersensitivity reactions were found in their red blood characteristics. In patients with hypersensitive reactions to drugs, significantly lower levels of erythrocytes and hemoglobin were found, while the median values of these parameters did not exceed the limits of reference values. These differences persisted also in the analysis of hemoglobin values, analyzed with accounting for the age and sex of patients. The reduction of hemoglobin was not accompanied by an increase in bilirubin in these patients. Thus, this fact does not support the assumption about the drug-induced hemolysis as a main effect influencing the hematological parameters. Hemogram evaluation performed during 7–10 days after admission demonstrated a higher level of hemoglobin in both groups. The biochemical markers were not significantly distinguished except bilirubin and alkaline phosphatase which were higher in patients with food-induced hypersensitivity.	ru_RU
dc.language.iso	ru	ru_RU
dc.subject	Children	ru_RU
dc.subject	acute hypersensitivity	ru_RU
dc.subject	food	ru_RU
dc.subject		ru_RU
dc.title	Hematologic features of children and adolescent patients with acute hypersensitivity reactions on drugs and food	ru_RU
dc.type	Articles in international journals and collections	ru_RU