KFU. Card publication. Relationship between salivary markers of oxidative stress (OS) and different levels of control of bronchial asthma (BA).

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RELATIONSHIP BETWEEN SALIVARY MARKERS OF OXIDATIVE STRESS (OS) AND DIFFERENT LEVELS OF CONTROL OF BRONCHIAL ASTHMA (BA).

Form of presentation

Conference proceedings in international journals and collections

Year of publication

2019

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Authors, employees of KFU

Kubysheva Nailya Iskhakovna, author

Other authors

Eliseeva Tatyana , author

Glukhova M. , author

Izvolenskaya Marina , author

Khaletskaya Olga , author

Klimanov Igor , author

Kolegova Tatyana , author

Kurashina V , author

Murakaeva L. , author

Soodaeva Svetlana , author

Tush Elena , author

Bibliographic description in the original language

Klimanov, I. A., Soodaeva, S. K., Tush, E. V., Kubysheva, N. I., Izvolenskaya, M. N., Eliseeva, T. I., T.I. Kolegova, V.A. Kurashina, O.V. Khaletskaya, L.R. Murakaeva, Glukhova, M. V. (2019). Relationship between salivary markers of oxidative stress (OS) and different levels of control of bronchial asthma (BA). European Respiratory Journal 2019 54: PA1706.

Annotation

European Respiratory Journal 2019; 54: Suppl. 63

Keywords

Biomarkers, asthma - mechanism, children

The name of the journal

European Respiratory Journal 2019; 54: Suppl. 63

URL

https://erj.ersjournals.com/content/54/suppl_63/PA1706.abstract

Please use this ID to quote from or refer to the card

https://repository.kpfu.ru/eng/?p_id=244535&p_lang=2

Resource files

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Relationship_between_salivary_markers_of_oxidative_stress__OS__and_different_levels_of_control_of_BA.pdf	0,33	pdf	show / download

Full metadata record

Field DC	Value	Language
dc.contributor.author	Kubysheva Nailya Iskhakovna	ru_RU
dc.contributor.author	Eliseeva Tatyana	ru_RU
dc.contributor.author	Glukhova M.	ru_RU
dc.contributor.author	Izvolenskaya Marina	ru_RU
dc.contributor.author	Khaletskaya Olga	ru_RU
dc.contributor.author	Klimanov Igor	ru_RU
dc.contributor.author	Kolegova Tatyana	ru_RU
dc.contributor.author	Kurashina V	ru_RU
dc.contributor.author	Murakaeva L.	ru_RU
dc.contributor.author	Soodaeva Svetlana	ru_RU
dc.contributor.author	Tush Elena	ru_RU
dc.date.accessioned	2019-01-01T00:00:00Z	ru_RU
dc.date.available	2019-01-01T00:00:00Z	ru_RU
dc.date.issued	2019	ru_RU
dc.identifier.citation	Klimanov, I. A., Soodaeva, S. K., Tush, E. V., Kubysheva, N. I., Izvolenskaya, M. N., Eliseeva, T. I., T.I. Kolegova, V.A. Kurashina, O.V. Khaletskaya, L.R. Murakaeva, Glukhova, M. V. (2019). Relationship between salivary markers of oxidative stress (OS) and different levels of control of bronchial asthma (BA). European Respiratory Journal 2019 54: PA1706.	ru_RU
dc.identifier.uri	https://repository.kpfu.ru/eng/?p_id=244535&p_lang=2	ru_RU
dc.description.abstract	European Respiratory Journal 2019; 54: Suppl. 63	ru_RU
dc.description.abstract	Introduction: Nowedays more than half patients with BA have partly controlled and uncontrolled of disease despite modern strategies of therapy. One of possible reason of low control of BA may be increase of OS in patients with airway inflammation. Aims: investigation of systemic parametrs of OS in children with different levels of control of BA. Material and Methods: We investigate 145 children with BA, 83 boys and 62 girls, 5-17 years old ages, with controlled BA (n=92) and partly controlled and uncontrolled BA (n=53). Control group included 18 healthy children 5-15 years old. The quantitative indicators of OS such as maximum intensity of chemiluminescence (Imax) and S paramet�rs in the saliva were evaluated. Results: Patients with uncontrolled BA have high level salivary prooxidant activity - S paramet�rs (59,4 ? 7,85) and Imax (3,10 ? 0,34) saliva higher, that healthy children (14,54 ? 1,66 and 1,23 ? 0,12 S and Imax respectively) and patients with controlled BA (8,44 ? 1,25 � 0,45 ? 0,07 S and Imax respectively), F = 39,13, � < 0,0001 for S and F = 51,70, � < 0,0001 for Imax. In healthy group Imax/S ratio was more higher (0,091 ? 0,009), that in patients with BA, �<0,001). In parallel, in group with controlled BA Imax/S ratio was lower (0,056 ? 0,002), that in uncontrolled patients (0,064 ? 0,003), p=0,0084. Decrease CL intensivity of saliva in patients with controlled BA may be the result of a decrease in OS tension. Conclusion: We suppose, that CL parametrs of saliva can be used in assessment systemic OS in patients with BA and undirect estimation systemic aspects of allergic inflammation.	ru_RU
dc.language.iso	ru	ru_RU
dc.subject	Biomarkers	ru_RU
dc.subject	asthma - mechanism	ru_RU
dc.subject	children	ru_RU
dc.title	Relationship between salivary markers of oxidative stress (OS) and different levels of control of bronchial asthma (BA).	ru_RU
dc.type	Conference proceedings in international journals and collections	ru_RU