KFU. Card publication. Importance of local glycan heterogeneity for in vivo cancer targeting

KAZAN
FEDERAL UNIVERSITY

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- ES

IMPORTANCE OF LOCAL GLYCAN HETEROGENEITY FOR IN VIVO CANCER TARGETING

Form of presentation

Articles in international journals and collections

Year of publication

2021

Язык

английский

Authors, employees of KFU

Tanaka Kacunori , author

Other authors

Nasibullin Igor Olegovich, author

Authors, postgraduates KFU

Smirnov Ivan Sergeevich, postgraduate kfu

Bibliographic description in the original language

Smirnov, I. Importance of local glycan heterogeneity for in vivo cancer targeting / I. Smirnov, I. Nasibullin, A. Kurbangalieva, K. Tanaka // Tetrahedron Lett. - 2021. - V. 72. - Art. № 153089.

Annotation

The preparation of heterogeneous glycoclusters on human serum albumin, containing two structurally non-identical N-glycans, is reported. In agreement with the cell-based interaction data, the trivial structural difference in local glycan heterogeneity can affect the in vivo distribution and cancer accumulation.

Keywords

N-glycan, Targeting, RIKEN click reaction, Albumin, 6π-Azaelectrocyclization

The name of the journal

Tetrahedron Letters

URL

https://www.sciencedirect.com/science/article/pii/S0040403921002914

Please use this ID to quote from or refer to the card

https://repository.kpfu.ru/eng/?p_id=252840&p_lang=2

Full metadata record

Field DC	Value	Language
dc.contributor.author	Tanaka Kacunori	ru_RU
dc.contributor.author	Nasibullin Igor Olegovich	ru_RU
dc.contributor.author	Smirnov Ivan Sergeevich	ru_RU
dc.date.accessioned	2021-01-01T00:00:00Z	ru_RU
dc.date.available	2021-01-01T00:00:00Z	ru_RU
dc.date.issued	2021	ru_RU
dc.identifier.citation	Smirnov, I. Importance of local glycan heterogeneity for in vivo cancer targeting / I. Smirnov, I. Nasibullin, A. Kurbangalieva, K. Tanaka // Tetrahedron Lett. - 2021. - V. 72. - Art. № 153089.	ru_RU
dc.identifier.uri	https://repository.kpfu.ru/eng/?p_id=252840&p_lang=2	ru_RU
dc.description.abstract	Tetrahedron Letters	ru_RU
dc.description.abstract	The preparation of heterogeneous glycoclusters on human serum albumin, containing two structurally non-identical N-glycans, is reported. In agreement with the cell-based interaction data, the trivial structural difference in local glycan heterogeneity can affect the in vivo distribution and cancer accumulation.	ru_RU
dc.language.iso	ru	ru_RU
dc.subject	N-glycan	ru_RU
dc.subject	Targeting	ru_RU
dc.subject	RIKEN click reaction	ru_RU
dc.subject	Albumin	ru_RU
dc.subject	6π-Azaelectrocyclization	ru_RU
dc.title	Importance of local glycan heterogeneity for in vivo cancer targeting	ru_RU
dc.type	Articles in international journals and collections	ru_RU