KFU. Card publication. О роли аутофагии в прогрессировании дифференцированного рака щитовидной железы (обзор литературы)

KAZAN
FEDERAL UNIVERSITY

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О РОЛИ АУТОФАГИИ В ПРОГРЕССИРОВАНИИ ДИФФЕРЕНЦИРОВАННОГО РАКА ЩИТОВИДНОЙ ЖЕЛЕЗЫ (ОБЗОР ЛИТЕРАТУРЫ)

Form of presentation

Articles in Russian journals and collections

Year of publication

2021

Язык

русский

Authors, employees of KFU

Abramova Zinaida Ivanovna, author

Other authors

Afanaseva Zinaida Aleksandrovna, author

Garipov Karim Albertovich, author

Bibliographic description in the original language

Garipov K.A. O roli autofagii v progressirovanii differencirovannogo raka shhitovidnoy zhelezy (obzor literatury) / K.A. Garipov, Z.A. Afanaseva, G.P. Semakov, Z.I. Abramova //Sibirskiy onkologicheskiy zhurnal.-2021.- T.20.- №6.- S.134-140(Q4)

Annotation

The aim of the study was to analyze and summarize available literature data on the role of autophagy in thyroid cancer. Material and methods. We analyzed 34 publications available from PubMed and eLIBRARY. RU databases concerning thyroid cancer and autophagy. Results. The review discussed the role of autophagy in the progression of thyroid cancer. The development of autophagy-targeted therapy was shown can improve treatment for thyroid cancer. Differentiated thyroid cancer (DTC) is the most common endocrine malignancy. Treatment of DTC patients who are resistant to radioactive iodine therapy is a major challenge. Molecular targeted therapy using tyrosine kinase inhibitors significantly improves treatment outcomes. Conclusion. To enhance the therapeutic effect of treatment with multi-target tyrosine kinase inhibitors, as well as to overcome drug resistance, it is necessary to study the role of autophagy in the development and progression of thyroid cancer.

Keywords

дифференцированный рак щитовидной железы, резистентность к противоопухолевой терапии, аутофагия, молекулярно-направленная терапия, ингибиторы тирозинкиназы

The name of the journal

СИБИРСКИЙ ОНКОЛОГИЧЕСКИЙ ЖУРНАЛ

URL

https://www.siboncoj.ru/jour/article/view/1996/939

Please use this ID to quote from or refer to the card

https://repository.kpfu.ru/eng/?p_id=253317&p_lang=2

Resource files

File name	Size (MB)	Format
O_ROLI_AUTOFAGII_V_PROGRESSIROVANII_RShhZh_Sibirskij_onkologicheskij_zh_l.pdf	0,51	pdf	show / download

Full metadata record

Field DC	Value	Language
dc.contributor.author	Abramova Zinaida Ivanovna	ru_RU
dc.contributor.author	Afanaseva Zinaida Aleksandrovna	ru_RU
dc.contributor.author	Garipov Karim Albertovich	ru_RU
dc.date.accessioned	2021-01-01T00:00:00Z	ru_RU
dc.date.available	2021-01-01T00:00:00Z	ru_RU
dc.date.issued	2021	ru_RU
dc.identifier.citation	Гарипов К.А. О роли аутофагии в прогрессировании дифференцированного рака щитовидной железы (обзор литературы) / К.А. Гарипов, З.А. Афанасьева, Г.П. Семаков, З.И. Абрамова //Сибирский онкологический журнал.-2021.- Т.20.- №6.- С.134-140(Q4)	ru_RU
dc.identifier.uri	https://repository.kpfu.ru/eng/?p_id=253317&p_lang=2	ru_RU
dc.description.abstract	СИБИРСКИЙ ОНКОЛОГИЧЕСКИЙ ЖУРНАЛ	ru_RU
dc.description.abstract	The aim of the study was to analyze and summarize available literature data on the role of autophagy in thyroid cancer. Material and methods. We analyzed 34 publications available from PubMed and eLIBRARY. RU databases concerning thyroid cancer and autophagy. Results. The review discussed the role of autophagy in the progression of thyroid cancer. The development of autophagy-targeted therapy was shown can improve treatment for thyroid cancer. Differentiated thyroid cancer (DTC) is the most common endocrine malignancy. Treatment of DTC patients who are resistant to radioactive iodine therapy is a major challenge. Molecular targeted therapy using tyrosine kinase inhibitors significantly improves treatment outcomes. Conclusion. To enhance the therapeutic effect of treatment with multi-target tyrosine kinase inhibitors, as well as to overcome drug resistance, it is necessary to study the role of autophagy in the development and progression of thyroid cancer.	ru_RU
dc.language.iso	ru	ru_RU
dc.subject	дифференцированный рак щитовидной железы	ru_RU
dc.subject	резистентность к противоопухолевой терапии	ru_RU
dc.subject	аутофагия	ru_RU
dc.subject	молекулярно-направленная терапия	ru_RU
dc.subject	ингибиторы тирозинкиназы	ru_RU
dc.title	О роли аутофагии в прогрессировании дифференцированного рака щитовидной железы (обзор литературы)	ru_RU
dc.type	Articles in Russian journals and collections	ru_RU