KFU. Card publication. Delimitation of the tick-borne flaviviruses. Resolving the tick-borne encephalitis virus and louping-ill virus paraphyletic taxa

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DELIMITATION OF THE TICK-BORNE FLAVIVIRUSES. RESOLVING THE TICK-BORNE ENCEPHALITIS VIRUS AND LOUPING-ILL VIRUS PARAPHYLETIC TAXA

Form of presentation

Articles in international journals and collections

Year of publication

2022

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Authors, employees of KFU

Tkachev Sergey Evgenevich, author

Bibliographic description in the original language

Bondaryuk et al., 2022. Delimitation of the tick-borne flaviviruses. Resolving the tick-borne encephalitis virus and louping-ill virus paraphyletic taxa // Molecular Phylogenetics and Evolution, ISSN: 1055-7903, Vol: 169, Page: 107411

Annotation

he tick-borne flavivirus (TBFV) group contains at least 12 members where five of them are important pathogens of humans inducing diseases with varying severity (from mild fever forms to acute encephalitis). The taxonomy structure of TBFV is not fully clarified at present. In particular, there is a number of paraphyletic issues of tick-borne encephalitis virus (TBEV) and louping-ill virus (LIV). In this study, we aimed to apply different bioinformatic approaches to analyze all available complete genome amino acid sequences to delineate TBFV members at the species level. Results showed that the European subtype of TBEV (TBEV-E) is a distinct species unit. LIV, in turn, should be separated into two species. Additional analysis of TBEV and LIV antigenic determinant diversity also demonstrate that TBEV-E and LIV are significantly different both from each other and from the other TBEV subtypes. The analysis of available literature provided data on other virus phenotypic particularities that supported our hypothesis. So, within the TBEV + LIV paraphyletic group, we offer to assign four species to get a more accurate understanding of the TBFV interspecies structure according to the modern monophyletic conception.

Keywords

TBFV, Species delimitation, Genomics, Phylogenetics

The name of the journal

Molecular Phylogenetics and Evolution

URL

https://www.sciencedirect.com/science/article/abs/pii/S1055790322000240?via%3Dihub

Please use this ID to quote from or refer to the card

https://repository.kpfu.ru/eng/?p_id=263121&p_lang=2

Full metadata record

Field DC	Value	Language
dc.contributor.author	Tkachev Sergey Evgenevich	ru_RU
dc.date.accessioned	2022-01-01T00:00:00Z	ru_RU
dc.date.available	2022-01-01T00:00:00Z	ru_RU
dc.date.issued	2022	ru_RU
dc.identifier.citation	Bondaryuk et al., 2022. Delimitation of the tick-borne flaviviruses. Resolving the tick-borne encephalitis virus and louping-ill virus paraphyletic taxa // Molecular Phylogenetics and Evolution, ISSN: 1055-7903, Vol: 169, Page: 107411	ru_RU
dc.identifier.uri	https://repository.kpfu.ru/eng/?p_id=263121&p_lang=2	ru_RU
dc.description.abstract	Molecular Phylogenetics and Evolution	ru_RU
dc.description.abstract	he tick-borne flavivirus (TBFV) group contains at least 12 members where five of them are important pathogens of humans inducing diseases with varying severity (from mild fever forms to acute encephalitis). The taxonomy structure of TBFV is not fully clarified at present. In particular, there is a number of paraphyletic issues of tick-borne encephalitis virus (TBEV) and louping-ill virus (LIV). In this study, we aimed to apply different bioinformatic approaches to analyze all available complete genome amino acid sequences to delineate TBFV members at the species level. Results showed that the European subtype of TBEV (TBEV-E) is a distinct species unit. LIV, in turn, should be separated into two species. Additional analysis of TBEV and LIV antigenic determinant diversity also demonstrate that TBEV-E and LIV are significantly different both from each other and from the other TBEV subtypes. The analysis of available literature provided data on other virus phenotypic particularities that supported our hypothesis. So, within the TBEV + LIV paraphyletic group, we offer to assign four species to get a more accurate understanding of the TBFV interspecies structure according to the modern monophyletic conception.	ru_RU
dc.language.iso	ru	ru_RU
dc.subject	TBFV	ru_RU
dc.subject	Species delimitation	ru_RU
dc.subject	Genomics	ru_RU
dc.subject	Phylogenetics	ru_RU
dc.title	Delimitation of the tick-borne flaviviruses. Resolving the tick-borne encephalitis virus and louping-ill virus paraphyletic taxa	ru_RU
dc.type	Articles in international journals and collections	ru_RU