KFU. Card publication. Numerical simulation of motility patterns of the small bowel. 1. Formulation of a mathematical model

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FEDERAL UNIVERSITY

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NUMERICAL SIMULATION OF MOTILITY PATTERNS OF THE SMALL BOWEL. 1. FORMULATION OF A MATHEMATICAL MODEL

Form of presentation

Articles in international journals and collections

Year of publication

1999

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Authors, employees of KFU

Abdyusheva Guzel Ravilevna, author

Other authors

Christensen James , author

Miftakhov Rustem Narimanovich, author

Bibliographic description in the original language

Abdusheva G.R. Numerical simulation of motility patterns of the small bowel. 1. Formulation of a mathematical model / RN Miftakhov, GR Abdusheva, J Christensen - Journal of theoretical biology, 1999 - Elsevier - 197 (1), 89-112

Annotation

A complete mathematical model of the periodic myoelectrical activity of a functional unit of the small intestine is presented. Based on real morphological and electrophysiological data, the model assumes that: the functional unit is an electromyogenic syncytium; the kinetics of L-type Ca2+, T-type Ca2+, Ca2+-activated K+, voltage dependent K+and Cl−channels determine the electrical activity of the functional unit; the enteric nervous system is satisfactorily represented by an efferent cholinergic neuron that provides an excitatory input to the functional unit through receptor-linked L-type Ca2+channels and by an afferent pathway composed of the primary and secondary sensory neurons; the dynamics of propagation of the wave of depolarization along the unmyelinated nerve axons satisfy the Hodgkin–Huxley model; the electrical activity of the neural soma reflects the interaction of N-type Ca2+channels, Ca2 …

Keywords

numerical simulation, mathematical model, motility patterns, Hodgkin?Huxley model, the electrical activity

The name of the journal

JOURNAL OF THEORETICAL BIOLOGY

URL

http://www.scopus.com/inward/record.url?eid=2-s2.0-0033531454&partnerID=MN8TOARS

Please use this ID to quote from or refer to the card

https://repository.kpfu.ru/eng/?p_id=266208&p_lang=2

Resource files

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Full metadata record

Field DC	Value	Language
dc.contributor.author	Abdyusheva Guzel Ravilevna	ru_RU
dc.contributor.author	Christensen James	ru_RU
dc.contributor.author	Miftakhov Rustem Narimanovich	ru_RU
dc.date.accessioned	1999-01-01T00:00:00Z	ru_RU
dc.date.available	1999-01-01T00:00:00Z	ru_RU
dc.date.issued	1999	ru_RU
dc.identifier.citation	Abdusheva G.R. Numerical simulation of motility patterns of the small bowel. 1. Formulation of a mathematical model / RN Miftakhov, GR Abdusheva, J Christensen - Journal of theoretical biology, 1999 - Elsevier - 197 (1), 89-112	ru_RU
dc.identifier.uri	https://repository.kpfu.ru/eng/?p_id=266208&p_lang=2	ru_RU
dc.description.abstract	JOURNAL OF THEORETICAL BIOLOGY	ru_RU
dc.description.abstract	A complete mathematical model of the periodic myoelectrical activity of a functional unit of the small intestine is presented. Based on real morphological and electrophysiological data, the model assumes that: the functional unit is an electromyogenic syncytium; the kinetics of L-type Ca2+, T-type Ca2+, Ca2+-activated K+, voltage dependent K+and Cl−channels determine the electrical activity of the functional unit; the enteric nervous system is satisfactorily represented by an efferent cholinergic neuron that provides an excitatory input to the functional unit through receptor-linked L-type Ca2+channels and by an afferent pathway composed of the primary and secondary sensory neurons; the dynamics of propagation of the wave of depolarization along the unmyelinated nerve axons satisfy the Hodgkin–Huxley model; the electrical activity of the neural soma reflects the interaction of N-type Ca2+channels, Ca2 …	ru_RU
dc.language.iso	ru	ru_RU
dc.subject	numerical simulation	ru_RU
dc.subject	mathematical model	ru_RU
dc.subject	motility patterns	ru_RU
dc.subject	Hodgkin?Huxley model	ru_RU
dc.subject	the electrical activity	ru_RU
dc.title	Numerical simulation of motility patterns of the small bowel. 1. Formulation of a mathematical model	ru_RU
dc.type	Articles in international journals and collections	ru_RU