Kazan (Volga region) Federal University, KFU
KAZAN
FEDERAL UNIVERSITY
 
SUBCONJUNCTIVAL USE OF MESENCHYMAL STEM CELLS FOR THE TREATMENT OF CANINE ULCERATIVE KERATITIS
Form of presentationArticles in Russian journals and collections
Year of publication2024
Языканглийский
  • Aymaletdinov Aleksandr Maazovich, author
  • Zakirova Elena Yurevna, author
  • Malaneva Albina Gennadevna, author
  • Rutland Catrine , author
  • Bibliographic description in the original language Valeeva A. N. Subconjunctival use of mesenchymal stem cells for the treatment of canine ulcerative keratitis / A. N. Valeeva, A. G. Malanyeva, C. S. Rutland [et al.] // Opera Medica et Physiologica. – 2024. – Vol. 11, No. 1. – P. 94-102. – DOI 10.24412/2500-2295-2024-1-94-102
    Annotation Ophthalmic diseases are common problems in dogs of various breeds and ages. In recent years, ophthalmologists have been paying more attention to stem cell (SC) therapies, since the renewal and regeneration of any tissue in the adult body depends on somatic SC, and eye tissues are no exception. The aim of the present work was to determine the influence of allogenic mesenchymal stem cells (MSC) in healing ulcerative keratitis of dogs. Our research showed that subconjunctival injections of allogeneic MSCs from adipose tissue was clinically safe for use in dogs during the follow-up period. These injections contributed to the decrease of the clinical manifestations of ulcerative keratitis in dogs, as evidenced by a decrease the intensity and area of the affected areas of the cornea compared to classic therapy.
    Keywords OPHTHALMIC DISEASES, ULCERATIVE KERATITIS, ALLOGENEIC MESENCHYMAL STEM CELLS, MSC TRANSPLANTATION, SUBCONJUNCTIVAL INJECTIONS, CELL THERAPY
    The name of the journal Opera Medica et Physiologica
    Please use this ID to quote from or refer to the card https://repository.kpfu.ru/eng/?p_id=315895&p_lang=2
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