KFU. Card publication. In Vivo Kinetics and Biodistribution Analysis of Neoglycoproteins: Effects of Chemically Introduced Glycans on Proteins

KAZAN
FEDERAL UNIVERSITY

- RUS
- 中文
- ES

IN VIVO KINETICS AND BIODISTRIBUTION ANALYSIS OF NEOGLYCOPROTEINS: EFFECTS OF CHEMICALLY INTRODUCED GLYCANS ON PROTEINS

Form of presentation

Articles in international journals and collections

Year of publication

2014

Authors, employees of KFU

Kurbangalieva Almira Rafaelovna, author

Other authors

A. Ogura

Bibliographic description in the original language

A. Ogura, A. Kurbangalieva, K. Tanaka. In Vivo Kinetics and Biodistribution Analysis of Neoglycoproteins: Effects of Chemically Introduced Glycans on Proteins // Glycoconj. Journal. 2014. V. 31. � 4. P. 273-279.

Annotation

Biodistribution and in vivo kinetics analysis of chemically prepared neoglycoproteins are reviewed. Various mono- and oligosaccharides were conjugated onto the protein surface by use of chemical methods. Their kinetic and organ-specific accumulation have extensively been studied after intravenous injection and analyzed by conventional dissection studies, as well as noninvasive methods, such as SPECT, PET, or fluorescence imaging. These studies clearly show the glycan-structure dependency on protein kinetics, which will provide promising possibilities for pharmacological and diagnostic applications.

Keywords

Neoglycoprotein, Bioconjugation, Chemical reaction, N-Glycans, Albumin, In vivo imaging, Tumor targeting, Biodistribution

The name of the journal

Glycoconjugate Journal

URL

http://link.springer.com/article/10.1007/s10719-014-9520-3

Please use this ID to quote from or refer to the card

https://repository.kpfu.ru/eng/?p_id=86952&p_lang=2

Full metadata record

Field DC	Value	Language
dc.contributor.author	Kurbangalieva Almira Rafaelovna	ru_RU
dc.date.accessioned	2014-01-01T00:00:00Z	ru_RU
dc.date.available	2014-01-01T00:00:00Z	ru_RU
dc.date.issued	2014	ru_RU
dc.identifier.citation	A. Ogura, A. Kurbangalieva, K. Tanaka. In Vivo Kinetics and Biodistribution Analysis of Neoglycoproteins: Effects of Chemically Introduced Glycans on Proteins // Glycoconj. Journal. 2014. V. 31. � 4. P. 273-279.	ru_RU
dc.identifier.uri	https://repository.kpfu.ru/eng/?p_id=86952&p_lang=2	ru_RU
dc.description.abstract	Glycoconjugate Journal	ru_RU
dc.description.abstract	Biodistribution and in vivo kinetics analysis of chemically prepared neoglycoproteins are reviewed. Various mono- and oligosaccharides were conjugated onto the protein surface by use of chemical methods. Their kinetic and organ-specific accumulation have extensively been studied after intravenous injection and analyzed by conventional dissection studies, as well as noninvasive methods, such as SPECT, PET, or fluorescence imaging. These studies clearly show the glycan-structure dependency on protein kinetics, which will provide promising possibilities for pharmacological and diagnostic applications.	ru_RU
dc.language.iso	ru	ru_RU
dc.subject	Neoglycoprotein	ru_RU
dc.subject	Bioconjugation	ru_RU
dc.subject	Chemical reaction	ru_RU
dc.subject	N-Glycans	ru_RU
dc.subject	Albumin	ru_RU
dc.subject	In vivo imaging	ru_RU
dc.subject	Tumor targeting	ru_RU
dc.subject	Biodistribution	ru_RU
dc.title	In Vivo Kinetics and Biodistribution Analysis of Neoglycoproteins: Effects of Chemically Introduced Glycans on Proteins	ru_RU
dc.type	Articles in international journals and collections	ru_RU