Form of presentation | Articles in international journals and collections |
Year of publication | 2014 |
|
Kurbangalieva Almira Rafaelovna, author
|
Other authors |
A. Ogura |
Bibliographic description in the original language |
A. Ogura, A. Kurbangalieva, K. Tanaka. Chemical Glycan Conjugation Controls the Biodistribution and Kinetics of Proteins in Live Animals // Mini-Rev. Med. Chem. 2014. V. 14. № 13. P. 1072–1077. |
Annotation |
The biodistributions and in vivo kinetics of chemically prepared neoglycoproteins have been examined previously and are reviewed here. A variety of mono- and oligosaccharides may be conjugated onto a protein surface using chemical methods. The kinetics and organ-specific accumulation profiles of these glycoconjugates, introduced through intravenous injection, have been analyzed using conventional dissection studies as well as noninvasive methods, such as SPECT, PET, or fluorescence imaging. These studies have revealed glycan-dependent protein distribution kinetics that may be useful for pharmacological and diagnostic applications. |
Keywords |
Albumin, bioconjugation, biodistribution, chemical reaction, in vivo imaging, neoglycoprotein, N-glycans, tumor targeting. |
The name of the journal |
MINI-REV MEDCHEM
|
URL |
http://benthamscience.com/journal/abstracts.php?journalID=mrmc&articleID=126443 |
Please use this ID to quote from or refer to the card |
https://repository.kpfu.ru/eng/?p_id=94721&p_lang=2 |
Full metadata record ![](https://shelly.kpfu.ru/pdf/picture/arrow_black_right.gif) |
Field DC |
Value |
Language |
dc.contributor.author |
Kurbangalieva Almira Rafaelovna |
ru_RU |
dc.date.accessioned |
2014-01-01T00:00:00Z |
ru_RU |
dc.date.available |
2014-01-01T00:00:00Z |
ru_RU |
dc.date.issued |
2014 |
ru_RU |
dc.identifier.citation |
A. Ogura, A. Kurbangalieva, K. Tanaka. Chemical Glycan Conjugation Controls the Biodistribution and Kinetics of Proteins in Live Animals // Mini-Rev. Med. Chem. 2014. V. 14. № 13. P. 1072–1077. |
ru_RU |
dc.identifier.uri |
https://repository.kpfu.ru/eng/?p_id=94721&p_lang=2 |
ru_RU |
dc.description.abstract |
MINI-REV MEDCHEM |
ru_RU |
dc.description.abstract |
The biodistributions and in vivo kinetics of chemically prepared neoglycoproteins have been examined previously and are reviewed here. A variety of mono- and oligosaccharides may be conjugated onto a protein surface using chemical methods. The kinetics and organ-specific accumulation profiles of these glycoconjugates, introduced through intravenous injection, have been analyzed using conventional dissection studies as well as noninvasive methods, such as SPECT, PET, or fluorescence imaging. These studies have revealed glycan-dependent protein distribution kinetics that may be useful for pharmacological and diagnostic applications. |
ru_RU |
dc.language.iso |
ru |
ru_RU |
dc.subject |
Albumin |
ru_RU |
dc.subject |
bioconjugation |
ru_RU |
dc.subject |
biodistribution |
ru_RU |
dc.subject |
chemical reaction |
ru_RU |
dc.subject |
in vivo imaging |
ru_RU |
dc.subject |
neoglycoprotein |
ru_RU |
dc.subject |
N-glycans |
ru_RU |
dc.subject |
tumor targeting. |
ru_RU |
dc.title |
Chemical Glycan Conjugation Controls the Biodistribution and Kinetics of Proteins in Live Animals |
ru_RU |
dc.type |
Articles in international journals and collections |
ru_RU |
|